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dc.contributor.authorKelly, Sarahen
dc.contributor.authorOlanrewaju, Oen
dc.contributor.authorCowan, Andrewen
dc.contributor.authorBrayne, Carolen
dc.contributor.authorLafortune, Louiseen
dc.date.accessioned2017-07-14T08:25:18Z
dc.date.available2017-07-14T08:25:18Z
dc.date.issued2017-07-20en
dc.identifier.issn0002-0729
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/265357
dc.description.abstractBackground harmful alcohol consumption is reported to be increasing in older people. To intervene and reduce associated risks, evidence currently available needs to be identified. Methods two systematic reviews in older populations (55+ years): (1) Interventions to prevent or reduce excessive alcohol consumption; (2) Interventions as (1) also reporting cognitive and dementia outcomes. Comprehensive database searches from 2000 to November 2016 for studies in English, from OECD countries. Alcohol dependence treatment excluded. Data were synthesised narratively and using meta-analysis. Risk of bias was assessed using NICE methodology. Reviews are reported according to PRISMA. Results thirteen studies were identified, but none with cognition or dementia outcomes. Three related to primary prevention; 10 targeted harmful or hazardous older drinkers. A complex range of interventions, intensity and delivery was found. There was an overall intervention effect for 3- and 6-month outcomes combined (8 studies; 3,591 participants; pooled standard mean difference (SMD) −0.18 (95% CI −0.28, −0.07) and 12 months (6 studies; 2,788 participants SMD −0.16 (95% CI −0.32, −0.01) but risk of bias for most studies was unclear with significant heterogeneity. Limited evidence (three studies) suggested more intensive interventions with personalised feedback, physician advice, educational materials, follow-up could be most effective. However, simple interventions including brief interventions, leaflets, alcohol assessments with advice to reduce drinking could also have a positive effect. Conclusions alcohol interventions in older people may be effective but studies were at unclear or high risk of bias. Evidence gaps include primary prevention, cost-effectiveness, impact on cognitive and dementia outcomes.
dc.description.sponsorshipThis paper presents independent research funded by the NIHR School for Public Health Research Ageing Well Programme and the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) East of England.
dc.language.isoenen
dc.publisherOxford University Press
dc.rightsAttribution-NonCommercial 4.0 Internationalen
dc.rightsAttribution-NonCommercial 4.0 Internationalen
dc.rightsAttribution-NonCommercial 4.0 Internationalen
dc.rightsAttribution-NonCommercial 4.0 Internationalen
dc.rightsAttribution-NonCommercial 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.rights.urihttp://creativecommons.org/licenses/by-nc/4.0/en
dc.subjectalcoholen
dc.subjectsystematic reviewen
dc.subjectolder peopleen
dc.subjectinterventionsen
dc.subjectdementiaen
dc.titleInterventions to prevent and reduce excessive alcohol consumption in older people: a systematic review and meta-analysisen
dc.typeArticle
prism.publicationDate2017en
prism.publicationNameAge and Ageingen
dc.identifier.doi10.17863/CAM.11387
dcterms.dateAccepted2017-06-29en
rioxxterms.versionofrecord10.1093/ageing/afx132en
rioxxterms.versionAMen
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by-nc/4.0/en
rioxxterms.licenseref.startdate2017-07-20en
dc.contributor.orcidKelly, Sarah [0000-0002-1114-2456]
dc.contributor.orcidCowan, Andrew [0000-0002-8981-5673]
dc.contributor.orcidBrayne, Carol [0000-0001-5307-663X]
dc.contributor.orcidLafortune, Louise [0000-0002-9018-1217]
dc.identifier.eissn1468-2834
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idDepartment of Health (via National Institute for Health Research (NIHR)) (unknown)
pubs.funder-project-idNational Institute for Health Research (NIHR) (via Cambridgeshire and Peterborough NHS Foundation Trust (CPFT) (unknown)
cam.orpheus.successThu Jan 30 12:53:32 GMT 2020 - Embargo updated*
rioxxterms.freetoread.startdate2018-07-20


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Attribution-NonCommercial 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial 4.0 International