Factors associated with glycemic control during free-living overnight closed-loop insulin delivery in children and adults with type 1 diabetes
Published version
Peer-reviewed
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Authors
Thabit, Hood
Leelarathna, Lalantha
Elleri, Daniela
Allen, Janet Macdonald
Abstract
Unsupervised free-living overnight home use of closed-loop insulin delivery is feasible, safe, and effective in adolescents1 and adults2 with type 1 diabetes, but outcomes vary between individuals. Understanding factors influencing glucose outcomes may help to identify vulnerable populations, guide design of future studies, and lead to enhanced control algorithms.
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Keywords
closed-loop insulin delivery, glycemic control, home study, predictive factors, type 1 diabetes
Journal Title
Journal of Diabetes Science and Technology
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Volume Title
9
Publisher
SAGE Publications
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Sponsorship
NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (R01DK085621)
Cambridge University Hospitals NHS Foundation Trust (CUH) (Roman Hovorka)
Cambridge University Hospitals NHS Foundation Trust (CUH) (Roman Hovorka)
Funding for these studies was received from the JDRF (#22-2009-802) and Diabetes UK (BDA07/0003549), with additional support for the Artificial Pancreas work by National Institute of Diabetes and Digestive and Kidney Diseases (1R01DK085621), Wellcome Strategic Award (100574/Z/12/Z), and National Institute for Health Research Cambridge Biomedical Research Centre.