Three-dimensional black-blood multi-contrast carotid imaging using compressed sensing: a repeatability study
Magnetic Resonance Materials in Physics, Biology, and Medicine
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Yuan, J., Usman, A., Reid, S., King, K., Patterson, A., Gillard, J., & Graves, M. (2017). Three-dimensional black-blood multi-contrast carotid imaging using compressed sensing: a repeatability study. Magnetic Resonance Materials in Physics, Biology, and Medicine https://doi.org/10.1007/s10334-017-0640-1
OBJECTIVE: The purpose of this work is to evaluate the repeatability of a compressed sensing (CS) accelerated multi-contrast carotid protocol at 3 T. MATERIALS AND METHODS: Twelve volunteers and eight patients with carotid disease were scanned on a 3 T MRI scanner using a CS accelerated 3-D black-blood multi-contrast protocol which comprises T1w, T2w and PDw without CS, and with a CS factor of 1.5 and 2.0. The volunteers were scanned twice, the lumen/wall area and wall thickness were measured for each scan. Eight patients were scanned once, the inter/intra-observer reproducibility of the measurements was calculated. RESULTS: In the repeated volunteer scans, the interclass correlation coefficient (ICC) for the wall area measurement using a CS factor of 1.5 in PDw, T1w and T2w were 0.95, 0.81, and 0.97, respectively. The ICC for lumen area measurement using a CS factor of 1.5 in PDw, T1w and T2w were 0.96, 0.92, and 0.96, respectively. In patients, the ICC for inter/intra-observer measurements of lumen/wall area, and wall thickness were all above 0.81 in all sequences. CONCLUSION: The results show a CS accelerated 3-D black-blood multi-contrast protocol is a robust and reproducible method for carotid imaging. Future protocol design could use CS to reduce the scanning time.
multi-contrast, carotid MRI, compressed sensing
The project was supported by the Addenbrooke’s Charitable Trust and the NIHR Comprehensive Biomedical Research Centre award to Cambridge University Hospitals NHS Foundation Trust in partnership with the University of Cambridge.
External DOI: https://doi.org/10.1007/s10334-017-0640-1
This record's URL: https://www.repository.cam.ac.uk/handle/1810/267311
Attribution 4.0 International
Licence URL: http://creativecommons.org/licenses/by/4.0/
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