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dc.contributor.authorBluck, Leslie
dc.contributor.authorWilliams, Rachel
dc.contributor.authorJackson, Sarah
dc.contributor.authorSalgin, Burak
dc.contributor.authorAcerini, Carlo
dc.contributor.authorDunger, David
dc.date.accessioned2017-10-03T07:44:58Z
dc.date.available2017-10-03T07:44:58Z
dc.date.issued2013-10-31
dc.identifier.citationLeslie Bluck, Rachel Williams, Sarah Jackson, Burak Salgin, Carlo Acerini, and David Dunger, “Insulin Sensitivity Assessed by Stable Isotopes with Oral Glucose Administration: Validation with Euglycaemic Clamp,” ISRN Endocrinology, vol. 2013, Article ID 189412, 7 pages, 2013. doi:10.1155/2013/189412
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/267612
dc.description.abstractMethods of determining insulin sensitivity that use an oral challenge of glucose are preferred to those using intravenous administration since the measurement is made in conditions more akin to normal physiology. One previously reported protocol (ODILE) studies glucose uptake in isolation from absorption and endogenous production by the intravenous administration of tracer approximately forty-five minutes after the oral dose is given. However, this methodology has not been validated against other accredited procedures. This study utilizes the euglycemic hyperinsulinemic clamp in order to validate the ODILE method.
dc.rightsAll Rights Reserveden
dc.rights.urihttps://www.rioxx.net/licenses/all-rights-reserved/en
dc.titleInsulin Sensitivity Assessed by Stable Isotopes with Oral Glucose Administration: Validation with Euglycaemic Clamp
dc.typeArticle
dc.date.updated2017-07-13T08:33:44Z
dc.description.versionPeer Reviewed
dc.language.rfc3066en
dc.rights.holderCopyright © 2013 Leslie Bluck et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.identifier.doi10.17863/CAM.13551
rioxxterms.versionofrecord10.1155/2013/189412


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