Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines.
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Authors
Karangwa, SA
Dutkowski, P
Fontes, P
Friend, PJ
Guarrera, JV
Markmann, JF
Minor, T
Quintini, C
Selzner, M
Uygun, K
Porte, RJ
Publication Date
2016-10Journal Title
Am J Transplant
ISSN
1600-6135
Publisher
Wiley
Volume
16
Issue
10
Pages
2932-2942
Language
eng
Type
Article
This Version
VoR
Physical Medium
Print-Electronic
Metadata
Show full item recordCitation
Karangwa, S., Dutkowski, P., Fontes, P., Friend, P., Guarrera, J., Markmann, J., Mergental, H., et al. (2016). Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines.. Am J Transplant, 16 (10), 2932-2942. https://doi.org/10.1111/ajt.13843
Abstract
With increasing demand for donor organs for transplantation, machine perfusion (MP) promises to be a beneficial alternative preservation method for donor livers, particularly those considered to be of suboptimal quality, also known as extended criteria donor livers. Over the last decade, numerous studies researching MP of donor livers have been published and incredible advances have been made in both experimental and clinical research in this area. With numerous research groups working on MP, various techniques are being explored, often applying different nomenclature. The objective of this review is to catalog the differences observed in the nomenclature used in the current literature to denote various MP techniques and the manner in which methodology is reported. From this analysis, we propose a standardization of nomenclature on liver MP to maximize consistency and to enable reliable comparison and meta-analyses of studies. In addition, we propose a standardized set of guidelines for reporting the methodology of future studies on liver MP that will facilitate comparison as well as clinical implementation of liver MP procedures.
Keywords
Humans, Organ Preservation, Liver Transplantation, Perfusion, Tissue Donors, Terminology as Topic, Meta-Analysis as Topic, Guidelines as Topic, Research Report
Sponsorship
Wellcome Trust (202077/Z/16/Z)
Evelyn Trust (unknown)
Identifiers
External DOI: https://doi.org/10.1111/ajt.13843
This record's URL: https://www.repository.cam.ac.uk/handle/1810/269389
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
Licence URL: http://creativecommons.org/licenses/by-nc-nd/4.0/
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