Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.
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Authors
Long, Lu
Yang, XuDong
Mueller, Matthias
Kinzel, Bernd
Yung, Lai Ming
Wilkinson, Janine
Moore, Stephen
Publication Date
2015-07Journal Title
Nature medicine
ISSN
1078-8956
Volume
21
Issue
7
Pages
777-785
Language
eng
Type
Article
This Version
AM
Physical Medium
Print-Electronic
Metadata
Show full item recordCitation
Long, L., Ormiston, M., Yang, X., Southwood, M., Graf, S., Machado, R. D., Mueller, M., et al. (2015). Selective enhancement of endothelial BMPR-II with BMP9 reverses pulmonary arterial hypertension.. Nature medicine, 21 (7), 777-785. https://doi.org/10.1038/nm.3877
Keywords
Pulmonary Artery, Heart Ventricles, Endothelial Cells, Animals, Mice, Inbred C57BL, Humans, Rats, Rats, Sprague-Dawley, Hypertension, Pulmonary, Monocrotaline, JNK Mitogen-Activated Protein Kinases, Immunoblotting, Densitometry, Gene Expression Profiling, Apoptosis, Cell Membrane Permeability, Transcription, Genetic, Phosphorylation, Aging, Systole, Male, Bone Morphogenetic Protein Receptors, Type II, Growth Differentiation Factor 2, Gene Knock-In Techniques
Sponsorship
British Heart Foundation (PG/10/35/28339)
British Heart Foundation (CH/09/001/25945)
British Heart Foundation (PG/11/10/28724)
British Heart Foundation (RG/13/4/30107)
MRC (MR/K020919/1)
MRC (G1000847)
British Heart Foundation (PG/12/54/29734)
MRC (G0800784)
Identifiers
External DOI: https://doi.org/10.1038/nm.3877
This record's URL: https://www.repository.cam.ac.uk/handle/1810/271025
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