Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.

Rodriguez, Raphaël; Miller, Kyle M; Forment, Josep; Bradshaw, Charles; Nikan, Mehran; Britton, Sébastien; Oelschlaegel, Tobias; Xhemalce, Blerta; Balasubramanian, Shankar; Jackson, Stephen

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Authors

Rodriguez, Raphaël

Miller, Kyle M

Forment, Josep

Bradshaw, Charles

Nikan, Mehran

Britton, Sébastien

Oelschlaegel, Tobias

Publication Date

2012-02-05

Journal Title

Nature chemical biology

ISSN

1552-4450

Volume

Issue

Pages

301-310

Language

eng

Type

Article

This Version

Physical Medium

Electronic

Metadata

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Citation

Rodriguez, R., Miller, K. M., Forment, J., Bradshaw, C., Nikan, M., Britton, S., Oelschlaegel, T., et al. (2012). Small-molecule-induced DNA damage identifies alternative DNA structures in human genes.. Nature chemical biology, 8 (3), 301-310. https://doi.org/10.1038/nchembio.780

Keywords

Tumor Cells, Cultured, Humans, Breast Neoplasms, DNA Damage, Picolinic Acids, Aminoquinolines, DNA, Antineoplastic Agents, Drug Screening Assays, Antitumor, Cell Cycle, Cell Proliferation, Structure-Activity Relationship, Molecular Weight, G-Quadruplexes

Sponsorship

Wellcome Trust (086861/Z/08/Z)

Cancer Research UK (11224)

BBSRC (BB/G008337/1)

Wellcome Trust (092096/Z/10/Z)

Identifiers

External DOI: https://doi.org/10.1038/nchembio.780

This record's URL: https://www.repository.cam.ac.uk/handle/1810/271071

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