Maize chlorotic mottle virus exhibits low divergence between differentiated regional sub-populations.
Authors
Quito-Avila, Diego F
Cabanas, Darlene
Bressan, Alberto
Wangai, Anne
Publication Date
2018-01-19Journal Title
Scientific reports
ISSN
2045-2322
Publisher
Nature Publishing Group
Volume
8
Issue
1
Pages
1173
Language
eng
Type
Article
This Version
VoR
Physical Medium
Electronic
Metadata
Show full item recordCitation
Braidwood, L., Quito-Avila, D. F., Cabanas, D., Bressan, A., Wangai, A., & Baulcombe, D. (2018). Maize chlorotic mottle virus exhibits low divergence between differentiated regional sub-populations.. Scientific reports, 8 (1), 1173. https://doi.org/10.1038/s41598-018-19607-4
Abstract
Maize chlorotic mottle virus has been rapidly spreading around the globe over the past decade. The interactions of maize chlorotic mottle virus with Potyviridae viruses causes an aggressive synergistic viral condition - maize lethal necrosis, which can cause total yield loss. Maize production in sub-Saharan Africa, where it is the most important cereal, is threatened by the arrival of maize lethal necrosis. We obtained maize chlorotic mottle virus genome sequences from across East Africa and for the first time from Ecuador and Hawaii, and constructed a phylogeny which highlights the similarity of Chinese to African isolates, and Ecuadorian to Hawaiian isolates. We used a measure of clustering, the adjusted Rand index, to extract region-specific SNPs and coding variation that can be used for diagnostics. The population genetics analysis we performed shows that the majority of sequence diversity is partitioned between populations, with diversity extremely low within China and East Africa.
Keywords
Gammaherpesvirinae, Computational Biology, Phylogeny, Plant Diseases, Base Sequence, Genotype, Polymorphism, Single Nucleotide, Genome, Viral, Genetic Variation, High-Throughput Nucleotide Sequencing, Geography, Medical
Sponsorship
BBSRC (1344406)
Embargo Lift Date
2100-01-01
Identifiers
External DOI: https://doi.org/10.1038/s41598-018-19607-4
This record's URL: https://www.repository.cam.ac.uk/handle/1810/273895
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