Regulating needs: Exploring the role of insulin-like growth factor-2 signalling in materno-fetal resource allocation.
Sferruzzi-Perri, Amanda Nancy
64 Suppl 1
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Sferruzzi-Perri, A. N. (2018). Regulating needs: Exploring the role of insulin-like growth factor-2 signalling in materno-fetal resource allocation.. Placenta, 64 Suppl 1 S16-S22. https://doi.org/10.1016/j.placenta.2018.01.005
During pregnancy, the fetus requires nutrients supplied by the mother to grow and develop. However, the mother also requires sufficient resources to support the pregnancy, as well as, to maintain her health. Failure to regulate resource allocation between the mother and fetus can lead to pregnancy complications with immediate and life-long consequences for maternal and offspring health. This review explores the role of insulin-like growth factor (IGF)-2 in regulating materno-fetal resource allocation, particularly via its regulation of placental development and function.
Placenta, Animals, Humans, Insulin-Like Growth Factor II, Signal Transduction, Pregnancy, Maternal-Fetal Exchange, Placentation, Female
External DOI: https://doi.org/10.1016/j.placenta.2018.01.005
This record's URL: https://www.repository.cam.ac.uk/handle/1810/274062