Cognitive impairment in Parkinson's disease: impact on quality of life of carers.
ICICLE-PD study group,
International journal of geriatric psychiatry
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Lawson, R., Yarnall, A., Johnston, F., Duncan, G., Khoo, T., Collerton, D., Taylor, J., et al. (2017). Cognitive impairment in Parkinson's disease: impact on quality of life of carers.. International journal of geriatric psychiatry, 32 (12), 1362-1370. https://doi.org/10.1002/gps.4623
The quality of life (QoL) of informal caregivers of people with Parkinson's disease (PD) (PwP) can be affected by the caring role. Because of cognitive symptoms and diminished activities of daily living, in addition to the management of motor symptoms, carers of PwP and cognitive impairment may experience increased levels of burden and poorer QoL compared with carers of PwP without cognitive impairment. This study aimed to investigate the impact of cognitive impairment in PD upon QoL of carers. Methods Approximately 36 months after diagnosis, 66 dyadic couples of PwP and carers completed assessments. PwP completed a schedule of neuropsychological assessments and QoL measures; carers of PwP completed demographic questionnaires and assessments of QoL. Factor scores of attention, memory/executive function and global cognition, as derived by principal component analysis, were used to evaluate cognitive domains. Results Hierarchical regression analysis found lower Montreal Cognitive Assessment was a significant independent predictor of poorer carer QoL, in addition to number of hours spent caregiving, carer depression and PD motor severity. Attentional deficits accounted for the largest proportion of variance of carer QoL. Carers of PwP and dementia (n = 9) had significantly poorer QoL scores compared with PwP and mild cognitive impairment (n = 18) or normal cognition (n = 39) carers (p < 0.01). Conclusions Attentional deficits were the strongest predictor of carer QoL compared with other cognitive predictors. Carers for those with PD dementia reported the poorest QoL. Interventions such as respite or cognitive behavioural therapy to improve mood and self‐efficacy in carers may improve carer QoL.
ICICLE-PD study group, Humans, Parkinson Disease, Activities of Daily Living, Regression Analysis, Cognition Disorders, Neuropsychological Tests, Quality of Life, Adult, Aged, Aged, 80 and over, Middle Aged, Female, Male, Surveys and Questionnaires
WELLCOME TRUST (103838/Z/14/Z)
Medical Research Council (MC_U105597119)
External DOI: https://doi.org/10.1002/gps.4623
This record's URL: https://www.repository.cam.ac.uk/handle/1810/274815
Attribution 4.0 International
Licence URL: http://creativecommons.org/licenses/by/4.0/
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