Research data supporting "A quantitative comparison of in-line coating thickness distributions obtained from a pharmaceutical tablet mixing process using discrete element method and terahertz pulsed imaging"
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In this compressed .zip file, the open data is provide to reproduce the data on the paper: A quantitative comparison of in-line coating thickness distributions obtained from a pharmaceutical tablet mixing process using discrete element method and terahertz pulsed imaging. The data can be divided into 3 categories: DEM input files are used to generate the dynamics of tablets in drum mixing; Ray-tracing codes and input files use the position and orientation of tablets to model the terahertz in-line sensing process; .m files are Matlab scripts for data analysis
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In this folder, the open data is provide to reproduce the data on the paper: A quantitative comparison of in-line coating thickness distributions obtained from a pharmaceutical tablet mixing process using discrete element method and terahertz pulsed imaging
1. Discrete element method
1.1 modified files
The discrete element method is run using LIGGGHTS version 3.1.0. Several files are modified to implement the multi-sphere method. The modified file are in the "DEM_liggghts_modified_files" folder. To run the simulations, the modified file should be used to replace the files with the same name in the "src" folder.
1.2 input file
Examples of input files for discrete element method is in the "DEM_inputfiles" folder, including mixing simulations with 1, 3 and 6 baffles. The input file is "drum.inp".
1.3 output file
The output files will be generated during the simulation into "post" folder. The output file will be "dump" files of liggghts (lammps). "lpp" can be used to convert these "dump" files into "vtk" files,
2. Ray-tracing method
2.1 The code
The code is in "codes" folder, which is compiled under Ubuntu 14.04 lts and GNU g++. To run the code, use:
./rayc < input
3.2 Input & output files
The example of input file is in "input_output" folder. The "input" is commented with explanations of each keywords. The output file can be generated into the specified folder.
4. Matlab data analysis
4.1 M file
The Matlab script files (M files) in Matlab/Mfiles are used to generate figures. Most script files use the ouptput from ray-tracing method to analyse data. So the path of the input/output files from these methods need to be changed in the related M files.
4.2 Figures
Figures related with data analysis are inlcluded in Matlab/figures folder.
Keywords
Terahertz in-line sensing, Terahertz pulsed imaging, Coating thickness variability, Discrete element method, Pharmaceutical coating
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Engineering and Physical Sciences Research Council (EP/L019922/1)