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dc.contributor.authorZhong, Yujie
dc.contributor.authorCook, Richard J
dc.date.accessioned2018-07-04T08:48:13Z
dc.date.available2018-07-04T08:48:13Z
dc.date.issued2019-04
dc.identifier.issn1380-7870
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/277785
dc.description.abstractThere have been many advances in statistical methodology for the analysis of recurrent event data in recent years. Multiplicative semiparametric rate-based models are widely used in clinical trials, as are more general partially conditional rate-based models involving event-based stratification. The partially conditional model provides protection against extra-Poisson variation as well as event-dependent censoring, but conditioning on outcomes post-randomization can induce confounding and compromise causal inference. The purpose of this article is to examine the consequences of model misspecification in semiparametric marginal and partially conditional rate-based analysis through omission of prognostic variables. We do so using estimating function theory and empirical studies.
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherSpringer Science and Business Media LLC
dc.rightsAttribution 4.0 International
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectHumans
dc.subjectRecurrence
dc.subjectData Interpretation, Statistical
dc.subjectModels, Statistical
dc.subjectMarkov Chains
dc.subjectSensitivity and Specificity
dc.subjectBiometry
dc.subjectData Accuracy
dc.subjectData Analysis
dc.titleThe effect of omitted covariates in marginal and partially conditional recurrent event analyses.
dc.typeArticle
prism.endingPage300
prism.issueIdentifier2
prism.publicationDate2019
prism.publicationNameLifetime Data Anal
prism.startingPage280
prism.volume25
dc.identifier.doi10.17863/CAM.25123
dcterms.dateAccepted2018-03-19
rioxxterms.versionofrecord10.1007/s10985-018-9430-y
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2019-04
dc.contributor.orcidZhong, Yujie [0000-0002-4448-2932]
dc.identifier.eissn1572-9249
rioxxterms.typeJournal Article/Review
pubs.funder-project-idMRC (unknown)
cam.issuedOnline2018-05-16
cam.orpheus.successThu Jan 30 12:58:16 GMT 2020 - The item has an open VoR version.
rioxxterms.freetoread.startdate2100-01-01


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International