Accuracy of death certification of dementia in population-based samples of older people: analysis over time.
Medical Research Council Cognitive Function and Ageing Collaboration,
Age and ageing
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Gao, L., Calloway, R., Zhao, E., Brayne, C., Matthews, F., & Medical Research Council Cognitive Function and Ageing Collaboration,. (2018). Accuracy of death certification of dementia in population-based samples of older people: analysis over time.. Age and ageing, 47 (4), 589-594. https://doi.org/10.1093/ageing/afy068
Objective To investigate the reliability of using death certificates for surveillance of dementia, the time trend of recording dementia on death certificates, and predictive factors of recording of dementia. Subjects Individuals aged 65 and over in six areas cross England and Wales were random selected for the Medical Research Council Cognitive Function and Ageing Study (CFAS) and CFAS II with mortality follow-up. Methods Prevalence of dementia recorded on death certificates were calculated by year. Reporting of dementia on death certificates compared with the study diagnosis of dementia, with sensitivity, specificity and Cohen’s κ estimated. Multivariable logistic regression models explored the impact of potential factors on the reporting of dementia on the death certificate. Results: The overall unadjusted prevalence of dementia on death certificates rose from 5.3% to 25.9% over the last 26 years. Dementia reported on death certificates was poor with sensitivity 21.0% in earlier cohort CFAS, but it had increased to 45.2% in CFAS II. Dementia was more likely to be recorded on death certificates in individuals with severe dementia, or those living in an institution, yet less likely reported if individuals died in hospital. Conclusion: Recording dementia on death certificate has improved significantly in England and Wales. However such information is still an underestimate and should be used alongside epidemiological estimations.
Medical Research Council Cognitive Function and Ageing Collaboration, Humans, Dementia, Death Certificates, Prevalence, Cause of Death, Risk Assessment, Risk Factors, Longitudinal Studies, Age Factors, Aging, Time Factors, Aged, Aged, 80 and over, England, Wales, Female, Male
External DOI: https://doi.org/10.1093/ageing/afy068
This record's URL: https://www.repository.cam.ac.uk/handle/1810/277935