Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.

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Authors
Gale, Davina
  Lawson, Andrew
Howarth, Karen
Madi, Mikidache
Durham, Bradley
Smalley, Sarah
Calaway, John
Publication Date
2018-01
Journal Title
PloS one
ISSN
1932-6203
Volume
13
Issue
3
Pages
e0194630
Language
eng
Type
Article
This Version
VoR
Physical Medium
Electronic-eCollection
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Citation
Gale, D., Lawson, A., Howarth, K., Madi, M., Durham, B., Smalley, S., Calaway, J., et al. (2018). Development of a highly sensitive liquid biopsy platform to detect clinically-relevant cancer mutations at low allele fractions in cell-free DNA.. PloS one, 13 (3), e0194630. https://doi.org/10.1371/journal.pone.0194630
Keywords
Humans, Neoplasms, DNA, Neoplasm, Sensitivity and Specificity, Reproducibility of Results, Polymerase Chain Reaction, DNA Mutational Analysis, Mutation, Alleles, Adult, Female, Male, Neoplastic Cells, Circulating, High-Throughput Nucleotide Sequencing, Biomarkers, Tumor, Cell-Free Nucleic Acids, Liquid Biopsy, Circulating Tumor DNA
Sponsorship
Cancer Research UK (C14303/A17197)
Identifiers
External DOI: https://doi.org/10.1371/journal.pone.0194630
This record's URL: https://www.repository.cam.ac.uk/handle/1810/278127

Rights
Attribution 4.0 International
Licence URL: http://creativecommons.org/licenses/by/4.0/


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International