Linking axon transport to regeneration using in vitro laser axotomy.
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Publication Date
2018-03Journal Title
Neural Regen Res
ISSN
1673-5374
Publisher
Medknow
Volume
13
Issue
3
Pages
410-412
Language
eng
Type
Article
This Version
VoR
Physical Medium
Print
Metadata
Show full item recordCitation
Nieuwenhuis, B., & Eva, R. (2018). Linking axon transport to regeneration using in vitro laser axotomy.. Neural Regen Res, 13 (3), 410-412. https://doi.org/10.4103/1673-5374.228716
Abstract
Spinal cord injury has devastating consequences because adult
central nervous system (CNS) neurons do not regenerate their
axons after injury. Two key reasons for axon regeneration failure
are extrinsic inhibitory factors and a low intrinsic capacity
for axon regrowth. Research has therefore focused on overcoming
extrinsic growth inhibition, and enhancing intrinsic regeneration
capacity. Both of these issues will need to be addressed
to enable optimal repair of the injured spinal cord.
Sponsorship
Medical Research Council (MR/R004463/1)
Medical Research Council (G1000864)
Medical Research Council (MR/R004544/1)
Spinal Research (ISRT) (NRB110)
Identifiers
External DOI: https://doi.org/10.4103/1673-5374.228716
This record's URL: https://www.repository.cam.ac.uk/handle/1810/278136
Rights
Attribution-NonCommercial-ShareAlike 4.0 International
Licence URL: http://creativecommons.org/licenses/by-nc-sa/4.0/
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