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dc.contributor.authorZakrzewski, Jaceken
dc.contributor.authorSmalley, Adam Pen
dc.contributor.authorKabeshov, Mikhailen
dc.contributor.authorGaunt, Matthewen
dc.contributor.authorLapkin, Alexeien
dc.date.accessioned2018-09-05T12:45:04Z
dc.date.available2018-09-05T12:45:04Z
dc.date.issued2016-07en
dc.identifier.issn1433-7851
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/279472
dc.description.abstractA continuous-flow synthesis of aziridines by palladium-catalyzed C(sp(3) )-H activation is described. The new flow reaction could be combined with an aziridine-ring-opening reaction to give highly functionalized aliphatic amines through a consecutive process. A predictive mechanistic model was developed and used to design the C-H activation flow process and illustrates an approach towards first-principles design based on novel catalytic reactions.
dc.format.mediumPrint-Electronicen
dc.languageengen
dc.rightsAttribution 4.0 International (CC BY 4.0)
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleContinuous-Flow Synthesis and Derivatization of Aziridines through Palladium-Catalyzed C(sp(3) )-H Activation.en
dc.typeArticle
prism.endingPage8883
prism.issueIdentifier31en
prism.publicationDate2016en
prism.publicationNameAngewandte Chemie (International ed. in English)en
prism.startingPage8878
prism.volume55en
dc.identifier.doi10.17863/CAM.26846
dcterms.dateAccepted2016-05-03en
rioxxterms.versionofrecord10.1002/anie.201602483en
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserveden
rioxxterms.licenseref.startdate2016-07en
dc.contributor.orcidSmalley, Adam P [0000-0001-5120-8678]
dc.contributor.orcidGaunt, Matthew [0000-0002-7214-608X]
dc.contributor.orcidLapkin, Alexei [0000-0001-7621-0889]
dc.identifier.eissn1521-3773
rioxxterms.typeJournal Article/Reviewen
pubs.funder-project-idEngineering and Physical Sciences Research Council (EP/I00548X/1)


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Attribution 4.0 International (CC BY 4.0)
Except where otherwise noted, this item's licence is described as Attribution 4.0 International (CC BY 4.0)