Show simple item record

dc.contributor.authorSen, Abhijit
dc.contributor.authorPapadimitriou, Nikos
dc.contributor.authorLagiou, Pagona
dc.contributor.authorPerez-Cornago, Aurora
dc.contributor.authorTravis, Ruth C
dc.contributor.authorKey, Timothy J
dc.contributor.authorMurphy, Neil
dc.contributor.authorGunter, Marc
dc.contributor.authorFreisling, Heinz
dc.contributor.authorTzoulaki, Ioanna
dc.contributor.authorMuller, David C
dc.contributor.authorCross, Amanda J
dc.contributor.authorLopez, David S
dc.contributor.authorBergmann, Manuela
dc.contributor.authorBoeing, Heiner
dc.contributor.authorBamia, Christina
dc.contributor.authorKotanidou, Anastasia
dc.contributor.authorKarakatsani, Anna
dc.contributor.authorTjønneland, Anne
dc.contributor.authorKyrø, Cecilie
dc.contributor.authorOutzen, Malene
dc.contributor.authorRedondo, María-Luisa
dc.contributor.authorCayssials, Valerie
dc.contributor.authorChirlaque, Maria-Dolores
dc.contributor.authorBarricarte, Aurelio
dc.contributor.authorSánchez, Maria-Jose
dc.contributor.authorLarrañaga, Nerea
dc.contributor.authorTumino, Rosario
dc.contributor.authorGrioni, Sara
dc.contributor.authorPalli, Domenico
dc.contributor.authorCaini, Saverio
dc.contributor.authorSacerdote, Carlotta
dc.contributor.authorBueno-de-Mesquita, Bas
dc.contributor.authorKühn, Tilman
dc.contributor.authorKaaks, Rudolf
dc.contributor.authorNilsson, Lena Maria
dc.contributor.authorLandberg, Rikard
dc.contributor.authorWallström, Peter
dc.contributor.authorDrake, Isabel
dc.contributor.authorBech, Bodil Hammer
dc.contributor.authorOvervad, Kim
dc.contributor.authorAune, Dagfinn
dc.contributor.authorKhaw, Kay-Tee
dc.contributor.authorRiboli, Elio
dc.contributor.authorTrichopoulos, Dimitrios
dc.contributor.authorTrichopoulou, Antonia
dc.contributor.authorTsilidis, Konstantinos K
dc.date.accessioned2018-09-05T12:51:45Z
dc.date.available2018-09-05T12:51:45Z
dc.date.issued2019-01-15
dc.identifier.issn0020-7136
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/279657
dc.description.abstractThe epidemiological evidence regarding the association of coffee and tea consumption with prostate cancer risk is inconclusive, and few cohort studies have assessed these associations by disease stage and grade. We examined the associations of coffee (total, caffeinated and decaffeinated) and tea intake with prostate cancer risk in the European Prospective Investigation into Cancer and Nutrition. Among 142,196 men, 7,036 incident prostate cancer cases were diagnosed over 14 years of follow-up. Data on coffee and tea consumption were collected through validated country-specific food questionnaires at baseline. We used Cox proportional hazards regression models to compute hazard ratios (HRs) and 95% confidence intervals (CI). Models were stratified by center and age, and adjusted for anthropometric, lifestyle and dietary factors. Median coffee and tea intake were 375 and 106 mL/day, respectively, but large variations existed by country. Comparing the highest (median of 855 mL/day) versus lowest (median of 103 mL/day) consumers of coffee and tea (450 vs. 12 mL/day) the HRs were 1.02 (95% CI, 0.94-1.09) and 0.98 (95% CI, 0.90-1.07) for risk of total prostate cancer and 0.97 (95% CI, 0.79-1.21) and 0.89 (95% CI, 0.70-1.13) for risk of fatal disease, respectively. No evidence of association was seen for consumption of total, caffeinated or decaffeinated coffee or tea and risk of total prostate cancer or cancer by stage, grade or fatality in this large cohort. Further investigations are needed to clarify whether an association exists by different preparations or by concentrations and constituents of these beverages.
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherWiley
dc.subjectHumans
dc.subjectProstatic Neoplasms
dc.subjectDiet Surveys
dc.subjectIncidence
dc.subjectProportional Hazards Models
dc.subjectRisk Factors
dc.subjectCohort Studies
dc.subjectCoffee
dc.subjectTea
dc.subjectAdult
dc.subjectAged
dc.subjectMiddle Aged
dc.subjectEurope
dc.subjectMale
dc.titleCoffee and tea consumption and risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition.
dc.typeArticle
prism.endingPage250
prism.issueIdentifier2
prism.publicationDate2019
prism.publicationNameInt J Cancer
prism.startingPage240
prism.volume144
dc.identifier.doi10.17863/CAM.27025
dcterms.dateAccepted2018-05-08
rioxxterms.versionofrecord10.1002/ijc.31634
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2019-01
dc.contributor.orcidPerez-Cornago, Aurora [0000-0002-5652-356X]
dc.contributor.orcidMurphy, Neil [0000-0003-3347-8249]
dc.contributor.orcidKyrø, Cecilie [0000-0002-9083-8960]
dc.contributor.orcidPalli, Domenico [0000-0002-5558-2437]
dc.contributor.orcidSacerdote, Carlotta [0000-0002-8008-5096]
dc.contributor.orcidKühn, Tilman [0000-0001-7702-317X]
dc.contributor.orcidKaaks, Rudolf [0000-0003-3751-3929]
dc.contributor.orcidDrake, Isabel [0000-0002-6500-6310]
dc.contributor.orcidKhaw, Kay-Tee [0000-0002-8802-2903]
dc.contributor.orcidTsilidis, Konstantinos K [0000-0002-8452-8472]
dc.identifier.eissn1097-0215
rioxxterms.typeJournal Article/Review
pubs.funder-project-idMedical Research Council (G1000143)
cam.issuedOnline2018-11-16
rioxxterms.freetoread.startdate2019-06-26


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record