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dc.contributor.authorWilson, HJ
dc.contributor.authorKhokhar, Fahad
dc.contributor.authorEnoch, DA
dc.contributor.authorBrown, NM
dc.contributor.authorAhluwalia, J
dc.contributor.authorDougan, Gordon
dc.contributor.authorTörök, ME
dc.date.accessioned2018-09-29T06:08:59Z
dc.date.available2018-09-29T06:08:59Z
dc.date.issued2018-09
dc.identifier.issn0195-6701
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/282935
dc.description.abstractInfections with carbapenemase-producing Enterobacteriaceae (CPE) and vancomycin-resistant enterococci (VRE) are associated with increased morbidity and mortality, but the carriage rates of CRE and VRE among hospital inpatients are unknown. A point-prevalence survey was conducted to determine CPE and VRE carriage rates in hospitalized adults. Eight hundred and eighteen of 960 (85.2%) adult inpatients were invited to participate in the study. Of these, 595 patients (72.7%) consented and provided specimens. Of 540 samples tested, none were positive for CPE. One hundred and thirty of 540 (24.1%) samples were VRE positive, and 34 of 40 (85%) of wards had cases. Universal screening for CPE may not be cost-effective in low-prevalence settings, but targeted screening of high-risk patients should continue. The optimal screening strategy for VRE remains to be determined, as universal screening and isolation is not feasible in the study setting.
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherElsevier BV
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectHumans
dc.subjectEnterobacteriaceae Infections
dc.subjectGram-Positive Bacterial Infections
dc.subjectPrevalence
dc.subjectCarrier State
dc.subjectAdolescent
dc.subjectAdult
dc.subjectAged
dc.subjectAged, 80 and over
dc.subjectMiddle Aged
dc.subjectInpatients
dc.subjectHospitals, University
dc.subjectFemale
dc.subjectMale
dc.subjectYoung Adult
dc.subjectVancomycin-Resistant Enterococci
dc.subjectSurveys and Questionnaires
dc.subjectUnited Kingdom
dc.subjectCarbapenem-Resistant Enterobacteriaceae
dc.titlePoint-prevalence survey of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant enterococci in adult inpatients in a university teaching hospital in the UK.
dc.typeArticle
prism.endingPage39
prism.issueIdentifier1
prism.publicationDate2018
prism.publicationNameJ Hosp Infect
prism.startingPage35
prism.volume100
dc.identifier.doi10.17863/CAM.30298
dcterms.dateAccepted2018-06-27
rioxxterms.versionofrecord10.1016/j.jhin.2018.06.024
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2018-09
dc.contributor.orcidDougan, Gordon [0000-0003-0022-965X]
dc.identifier.eissn1532-2939
rioxxterms.typeJournal Article/Review
pubs.funder-project-idAcademy of Medical Sciences (unknown)
pubs.funder-project-idCambridge University Hospitals NHS Foundation Trust (CUH) (BRC)
pubs.funder-project-idMedical Research Council (MR/N029399/1)


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International