Show simple item record

dc.contributor.authorCrivelli-Decker, Jordan
dc.contributor.authorHsieh, Liang-Tien
dc.contributor.authorClarke, Alex
dc.contributor.authorRanganath, Charan
dc.date.accessioned2018-11-08T00:30:43Z
dc.date.available2018-11-08T00:30:43Z
dc.date.issued2018-09
dc.identifier.issn1074-7427
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/284744
dc.description.abstractMany theoretical models suggest that neural oscillations play a role in learning or retrieval of temporal sequences, but the extent to which oscillations support sequence representation remains unclear. To address this question, we used scalp electroencephalography (EEG) to examine oscillatory activity over learning of different object sequences. Participants made semantic decisions on each object as they were presented in a continuous stream. For three "Consistent" sequences, the order of the objects was always fixed. Activity during Consistent sequences was compared to "Random" sequences that consisted of the same objects presented in a different order on each repetition. Over the course of learning, participants made faster semantic decisions to objects in Consistent, as compared to objects in Random sequences. Thus, participants were able to use sequence knowledge to predict upcoming items in Consistent sequences. EEG analyses revealed decreased oscillatory power in the theta (4-7 Hz) band at frontal sites following decisions about objects in Consistent sequences, as compared with objects in Random sequences. The theta power difference between Consistent and Random only emerged in the second half of the task, as participants were more effectively able to predict items in Consistent sequences. Moreover, we found increases in parieto-occipital alpha (10-13 Hz) and beta (14-28 Hz) power during the pre-response period for objects in Consistent sequences, relative to objects in Random sequences. Linear mixed effects modeling revealed that single trial theta oscillations were related to reaction time for future objects in a sequence, whereas beta and alpha oscillations were only predictive of reaction time on the current trial. These results indicate that theta and alpha/beta activity preferentially relate to future and current events, respectively. More generally our findings highlight the importance of band-specific neural oscillations in the learning of temporal order information.
dc.description.sponsorshipThis work was supported by a Vannevar Bush Fellowship (Office of Naval Research Grant N00014-15-1-0033) and a Multi-University Research Initiative Grant (Office of Naval Research Grant N00014-17-1-2961) from the Office of Naval Research.
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherElsevier BV
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectBrain
dc.subjectHumans
dc.subjectTheta Rhythm
dc.subjectLearning
dc.subjectPattern Recognition, Visual
dc.subjectDecision Making
dc.subjectReaction Time
dc.subjectTime Factors
dc.subjectFemale
dc.subjectMale
dc.subjectBrain Waves
dc.titleTheta oscillations promote temporal sequence learning.
dc.typeArticle
prism.endingPage103
prism.issueIdentifierPt A
prism.publicationDate2018
prism.publicationNameNeurobiol Learn Mem
prism.startingPage92
prism.volume153
dc.identifier.doi10.17863/CAM.32116
dcterms.dateAccepted2018-05-09
rioxxterms.versionofrecord10.1016/j.nlm.2018.05.001
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2018-09
dc.contributor.orcidClarke, Alex [0000-0001-7768-5229]
dc.identifier.eissn1095-9564
rioxxterms.typeJournal Article/Review
cam.issuedOnline2018-05-17


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International