Show simple item record

dc.contributor.authorvon Krbek Promel, Larissa
dc.contributor.authorRoberts, Derrick
dc.contributor.authorPilgrim, Ben
dc.contributor.authorSchalley, Christoph A
dc.contributor.authorNitschke, Jonathan
dc.date.accessioned2018-11-17T00:31:25Z
dc.date.available2018-11-17T00:31:25Z
dc.date.issued2018-10-22
dc.identifier.issn1433-7851
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/285366
dc.description.abstractWe report a strategy for regulating the rate of internally bound anion exchange within an Fe4 L6 metal-organic tetrahedron through external coordination of tripodal tris(alkylammonium) cations. The cage features three flexible 18-crown-6 receptors at each of its FeII vertices, facilitating strong tritopic interactions with tris(ammonium) cations to "cap" the vertices of the tetrahedron. This capping mechanism restricts the flexibility of the cage framework, thereby reducing the rate of anion exchange within its central cavity by 20-fold. Thus, we demonstrate the first use of an externally bound multivalent effector to allosterically control internal guest binding in a molecular cage.
dc.description.sponsorshipUK Engineering and Physical Sciences Research Council (EPSRC EP/P027067/1), the European Research Council (695009), and the Deutsche Forschungsgemeinschaft (SFB 765)
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherWiley
dc.titleMultivalent Crown Ether Receptors Enable Allosteric Regulation of Anion Exchange in an Fe4 L6 Tetrahedron.
dc.typeArticle
prism.endingPage14124
prism.issueIdentifier43
prism.publicationDate2018
prism.publicationNameAngew Chem Int Ed Engl
prism.startingPage14121
prism.volume57
dc.identifier.doi10.17863/CAM.32733
dcterms.dateAccepted2018-09-03
rioxxterms.versionofrecord10.1002/anie.201808534
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2018-10
dc.contributor.orcidvon Krbek Promel, Larissa [0000-0002-4278-5235]
dc.contributor.orcidRoberts, Derrick [0000-0002-4663-7475]
dc.contributor.orcidPilgrim, Ben [0000-0002-3353-3327]
dc.contributor.orcidSchalley, Christoph A [0000-0002-8634-3578]
dc.contributor.orcidNitschke, Jonathan [0000-0002-4060-5122]
dc.identifier.eissn1521-3773
rioxxterms.typeJournal Article/Review
pubs.funder-project-idRoyal Commission for the Exhibition of 1851 (RF478/2016)
pubs.funder-project-idEngineering and Physical Sciences Research Council (EP/P027067/1)
pubs.funder-project-idEuropean Research Council (695009)
cam.issuedOnline2018-09-27
rioxxterms.freetoread.startdate2019-10-31


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record