Accelerating the estimation of 3D spatially resolved T2 distributions.
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Authors
Reci, A
de Kort, DW
Sederman, AJ
Gladden, LF
Publication Date
2018-11Journal Title
J Magn Reson
ISSN
1090-7807
Publisher
Elsevier BV
Volume
296
Pages
93-102
Language
eng
Type
Article
Physical Medium
Print-Electronic
Metadata
Show full item recordCitation
Reci, A., de Kort, D., Sederman, A., & Gladden, L. (2018). Accelerating the estimation of 3D spatially resolved T2 distributions.. J Magn Reson, 296 93-102. https://doi.org/10.1016/j.jmr.2018.08.008
Abstract
Obtaining quantitative, 3D spatially-resolved T2 distributions (T2 maps) from magnetic resonance data is of importance in both medical and porous media applications. Due to the long acquisition time, there is considerable interest in accelerating the experiments by applying undersampling schemes during the acquisition and developing reconstruction techniques for obtaining the 3D T2 maps from the undersampled data. A multi-echo spin echo pulse sequence is used in this work to acquire the undersampled data according to two different sampling patterns: a conventional coherent sampling pattern where the same set of lines in k-space is sampled for all equally-spaced echoes in the echo train, and a proposed incoherent sampling pattern where an independent set of k-space lines is sampled for each echo. The conventional reconstruction technique of total variation regularization is compared to the more recent techniques of nuclear norm regularization and Nuclear Total Generalized Variation (NTGV) regularization. It is shown that best reconstructions are obtained when the data acquired using an incoherent sampling scheme are processed using NTGV regularization. Using an incoherent sampling pattern and NTGV regularization as the reconstruction technique, quantitative results are obtained at sampling percentages as low as 3.1% of k-space, corresponding to a 32-fold decrease in the acquisition time, compared to a fully sampled dataset.
Sponsorship
Engineering and Physical Sciences Research Council (EP/K039318/1)
Identifiers
External DOI: https://doi.org/10.1016/j.jmr.2018.08.008
This record's URL: https://www.repository.cam.ac.uk/handle/1810/285606
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