Effect of Iron Levels on Women After Premature or Early-Onset Menopause-Reply.
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Publication Date
2017-04-01Journal Title
JAMA Cardiology
ISSN
2380-6583
Publisher
American Medical Association
Volume
2
Issue
4
Pages
458-459
Language
eng
Type
Article
Metadata
Show full item recordCitation
Muka, T., Chowdhury, R., & Franco, O. (2017). Effect of Iron Levels on Women After Premature or Early-Onset Menopause-Reply.. JAMA Cardiology, 2 (4), 458-459. https://doi.org/10.1001/jamacardio.2016.5084
Abstract
Our study showed that the early onset of menopause is associated with an increased risk of cardiovascular disease and mortality. We agree with Hayes et al as well as Mascitelli and Goldstein that elevated iron levels observed after menopause can be a potential mechanism linking the early onset of menopause with adverse cardiometabolic health. Iron is one of the most abundant metals in the human body and is required as an essential cofactor in many important biological processes, such as oxygen transport, DNA synthesis, energy production, and regulation of cell growth and differentiation.
Sponsorship
MRC (MR/L003120/1)
British Heart Foundation (RG/08/014/24067)
Identifiers
External DOI: https://doi.org/10.1001/jamacardio.2016.5084
This record's URL: https://www.repository.cam.ac.uk/handle/1810/286072
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