Recent advancements in the use of exosomes as drug delivery systems.
View / Open Files
Publication Date
2018-10-16Journal Title
J Nanobiotechnology
ISSN
1477-3155
Publisher
Springer Science and Business Media LLC
Volume
16
Issue
1
Pages
81
Language
eng
Type
Article
This Version
VoR
Physical Medium
Electronic
Metadata
Show full item recordCitation
Bunggulawa, E. J., Wang, W., Yin, T., Wang, N., Durkan, C., Wang, Y., & Wang, G. (2018). Recent advancements in the use of exosomes as drug delivery systems.. J Nanobiotechnology, 16 (1), 81. https://doi.org/10.1186/s12951-018-0403-9
Abstract
Extracellular vesicles (EVs) are the substances that are released by most types of cells and have an important role in cell to cell communication. Among the most highly researched EVs are exosome. Recent studies show that exosomes derived from cells have different roles and targets. Many studies show that exosome can efficiently deliver many different kinds of cargo to the target cell. Therefore, they are often used to deliver therapeutic cargo for treatment. The exosomes that have been used include both natural ones and those that have been modified with other substances to increase the delivery ability. This article provides a review of both exosomes derived from various cells and modified exosome and their ability in delivering the many kinds of cargo to the target cell.
Keywords
Animals, Humans, Neoplasms, Drug Delivery Systems, Hydrogen-Ion Concentration, Nanoparticles, Exosomes
Sponsorship
None
Identifiers
External DOI: https://doi.org/10.1186/s12951-018-0403-9
This record's URL: https://www.repository.cam.ac.uk/handle/1810/286375
Statistics
Total file downloads (since January 2020). For more information on metrics see the
IRUS guide.