A track of the clones: new developments in cellular barcoding.
Kent, David G
MetadataShow full item record
Lyne, A., Kent, D. G., Laurenti, E., Cornils, K., Glauche, I., & Perié, L. (2018). A track of the clones: new developments in cellular barcoding.. Exp Hematol, 68 15-20. https://doi.org/10.1016/j.exphem.2018.11.005
International experts from multiple disciplines gathered at Homerton College in Cambridge, UK from September 12-14, 2018 to consider recent advances and emerging opportunities in the clonal tracking of hematopoiesis in one of a series of StemCellMathLab workshops. The group included 35 participants with experience in the fields of theoretical and experimental aspects of clonal tracking, and ranged from doctoral students to senior professors. Data from a variety of model systems and from clinical gene therapy trials were discussed, along with strategies for data analysis and sharing and challenges arising due to underlying assumptions in data interpretation and communication. Recognizing the power of this technology underpinned a group consensus of a need for improved mechanisms for sharing data and analytical protocols to maintain reproducibility and rigor in its application to complex tissues.
Cell Lineage, Cell Separation, Cell Tracking, Clinical Trials as Topic, Clone Cells, DNA Barcoding, Taxonomic, DNA Transposable Elements, Data Display, Forecasting, Genetic Markers, Genetic Therapy, Guidelines as Topic, Hematopoiesis, Models, Biological, Mosaicism, Reproducibility of Results, Research Design, Stem Cells, Virus Integration
We thank the BBSRC (BB/R021465/1), the German Stem Cell Network, the Wellcome-MRC Cambridge Stem Cell Institute and the Labex CelTisPhyBio (No. ANR-10-LBX-0038) for funds to support this workshop and the conference staff at Homerton College
Biotechnology and Biological Sciences Research Council (BB/R021465/1)
Medical Research Council (MC_PC_12009)
European Research Council (715371)
External DOI: https://doi.org/10.1016/j.exphem.2018.11.005
This record's URL: https://www.repository.cam.ac.uk/handle/1810/287061
Recommended or similar items
The current recommendation prototype on the Apollo Repository will be turned off on 03 February 2023. Although the pilot has been fruitful for both parties, the service provider IKVA is focusing on horizon scanning products and so the recommender service can no longer be supported. We recognise the importance of recommender services in supporting research discovery and are evaluating offerings from other service providers. If you would like to offer feedback on this decision please contact us on: firstname.lastname@example.org