Persistence of Imported Malaria Into the United Kingdom: An Epidemiological Review of Risk Factors and At-risk Groups.
Moyo, Qubekani M
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
University of Chicago Press
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Moyo, Q. M., Besser, M., Lynn, R., & Lever, A. (2019). Persistence of Imported Malaria Into the United Kingdom: An Epidemiological Review of Risk Factors and At-risk Groups.. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 69 (7), 1156-1162. https://doi.org/10.1093/cid/ciy1037
Background: The UK documented a fall of over 30% in imported cases of malaria annually between 1996-2003 however there are still around 1700 cases and 5-10 deaths each year. Prophylaxis health messages focus on families returning to their country of origin as being at particular risk. Methods: We reviewed 225 paper records including demographic data of patients seen in Addenbrooke’s hospital (Cambridge University Hospital Foundation Trust – CUHFT) a tertiary referral centre in Cambridge, England. All the records of the patients seen in CUHFT over the period 2002-2016 were analysed and assessed in the context of national figures from Public Health England Results: Over the period 2004-2016 there was no perceptible decrease in imported cases of malaria locally or nationally. Local figures largely reflected national trends. P.falciparum remains responsible for most imported infections (66.7%), P.vivax contributed 15.1%, P.malariae 4%, P.ovale 6.7% and 7.5% (17/225) patients had an incomplete record. Most cases were reported in people coming from West Africa. Sierra Leone and the Ivory Coast had the highest proportions of travellers being infected at 8 and 7 per 1000 respectively. Visiting family in the country of origin (27.8%) was the most common reason to have travelled to malarious countries. However, this was exceeded by the combined numbers travelling for work reasons and holidays, 22.5% and 20.1% respectively. 60% of patients took no prophylaxis. Of those that did, none of the patients finished their chemoprophylaxis regime. Conclusions: A significant number of travellers to malarious countries still take no chemoprophylaxis. Health advice about prophylaxis pre-travel to malarious countries should be targeted not only at those visiting family in their country of origin but also to those travelling for holiday and work/business.
Humans, Plasmodium, Malaria, Population Surveillance, Risk Factors, Retrospective Studies, Seasons, Age Factors, Sex Factors, Travel, Adolescent, Adult, Aged, Aged, 80 and over, Middle Aged, Child, Child, Preschool, Infant, Female, Male, Young Adult, United Kingdom, Communicable Diseases, Imported
External DOI: https://doi.org/10.1093/cid/ciy1037
This record's URL: https://www.repository.cam.ac.uk/handle/1810/287362
Attribution-NonCommercial-NoDerivatives 4.0 International
Licence URL: https://creativecommons.org/licenses/by-nc-nd/4.0/