Personalized Treatment in Inflammatory Bowel Disease: For Another Time.
Kaneider, Nicole C
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Kaneider, N. C., & Kaser, A. (2018). Personalized Treatment in Inflammatory Bowel Disease: For Another Time.. Gastroenterology, 155 (4), 963-964. https://doi.org/10.1053/j.gastro.2018.09.004
For decades plagued by therapies of limited efficacy, the recent arrival of an embarrassment of riches in effective therapeutics for inflammatory bowel disease 1, 2 – likely to grow further in coming years 3-6 – has made personalization of therapy ever more urgent. Practicing physicians have no other option than to follow a rather mundane step-up and trial-and-error approach. The results of an exemplary biomarker trial conducted by Janssen and published in this issue 7 showcases how hard progress in this area is – and points to the sobering prospect that the current trial-and-error approach may stay for some longer.
Humans, Inflammatory Bowel Diseases
Research in the authors’ laboratory is supported by the Wellcome Trust (Investigator Award 106260/Z/14/Z to A.K. and career re-entry fellowship 103077/Z/13/Z to N.C.K.) and the European Research Council (ERC; under HORIZON2020/ERC Grant agreement no. 648889).
WELLCOME TRUST (106260/Z/14/Z)
ECH2020 EUROPEAN RESEARCH COUNCIL (ERC) (648889)
Wellcome Trust (103077/Z/13/Z)
External DOI: https://doi.org/10.1053/j.gastro.2018.09.004
This record's URL: https://www.repository.cam.ac.uk/handle/1810/287752