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A 3D cell shape that enables tube formation.

Accepted version
Peer-reviewed

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Type

Article

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Authors

Abstract

Sheets of cells called epithelia can curve into tubes in embryos. Modelling and in vivo observations reveal that cells in the tube adopt an asymmetric cell shape dubbed scutoid, contrary to some previous assumptions.

Description

Keywords

Biophysics, Developmental biology, Cell Shape, Epithelium, Histone Deacetylase Inhibitors, Morphogenesis

Journal Title

Nature

Conference Name

Journal ISSN

0028-0836
1476-4687

Volume Title

561

Publisher

Springer Science and Business Media LLC
Sponsorship
Wellcome Trust (099234/Z/12/Z)
Isaac Newton Trust (Minute 1523(k))
Wellcome Trust (207553/Z/17/Z)