Repository logo
 

Discussion of "Gene hunting with hidden Markov model knockoffs'

Published version
Peer-reviewed

Type

Article

Change log

Authors

Abstract

We congratulate the authors on this interesting paper that tackles the difficult problem of extending the work of Candès et al. (2018) to structured predictors possessing a particular type of dependence. Motivated by the aim of making the knockoff construction applicable to genome-wide association studies, Sesia et al. (2019) propose using a hidden Markov model to generate knockoffs that capture patterns of DNA variation, following the work of Scheet & Stephens (2006).

Description

Keywords

38 Economics, 4905 Statistics, 3802 Econometrics, 49 Mathematical Sciences

Journal Title

Biometrika

Conference Name

Journal ISSN

1464-3510
1464-3510

Volume Title

106

Publisher

Oxford University Press
Sponsorship
Engineering and Physical Sciences Research Council (EP/R018561/1)
MRC (Unknown)
Alan Turing Institute (Unknown)