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RNAcentral: a hub of information for non-coding RNA sequences.

Published version
Peer-reviewed

Type

Article

Change log

Authors

The RNAcentral Consortium 

Abstract

RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences, collating information on ncRNA sequences of all types from a broad range of organisms. We have recently added a new genome mapping pipeline that identifies genomic locations for ncRNA sequences in 296 species. We have also added several new types of functional annotations, such as tRNA secondary structures, Gene Ontology annotations, and miRNA-target interactions. A new quality control mechanism based on Rfam family assignments identifies potential contamination, incomplete sequences, and more. The RNAcentral database has become a vital component of many workflows in the RNA community, serving as both the primary source of sequence data for academic and commercial groups, as well as a source of stable accessions for the annotation of genomic and functional features. These examples are facilitated by an improved RNAcentral web interface, which features an updated genome browser, a new sequence feature viewer, and improved text search functionality. RNAcentral is freely available at https://rnacentral.org.

Description

Keywords

The RNAcentral Consortium

Journal Title

Nucleic Acids Res

Conference Name

Journal ISSN

0305-1048
1362-4962

Volume Title

47

Publisher

Oxford University Press (OUP)
Sponsorship
National Institutes of Health (NIH) (via Harvard University) (132626-5085854)
Biotechnology and Biological Sciences Research Council (BBSRC) [BB/N019199/1]. Funding for open access charge: Research Councils UK (RCUK).