Longitudinal population subgroups of CRP and risk of depression in the ALSPAC birth cohort.

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Authors
  Osimo, Emanuele F
  Stochl, Jan
  Zammit, Stan
  Lewis, Glyn
  Jones, Peter
  Khandaker, Golam
Publication Date
2020-01
Journal Title
Comprehensive psychiatry
ISSN
0010-440X
Publisher
Elsevier
Volume
96
Pages
152143
Language
eng
Type
Article
This Version
AM
Physical Medium
Print-Electronic
Metadata
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Citation
Osimo, E. F., Stochl, J., Zammit, S., Lewis, G., Jones, P., & Khandaker, G. (2020). Longitudinal population subgroups of CRP and risk of depression in the ALSPAC birth cohort.. Comprehensive psychiatry, 96 152143. https://doi.org/10.1016/j.comppsych.2019.152143
Abstract
Abstract Background Meta-analyses confirm increased circulating C-reactive protein (CRP) levels in depression. Longitudinal studies have linked one-off measurements of CRP at baseline with increased risk of developing depressive symptoms subsequently at follow-up, but studies with repeat CRP measures from the same individuals are scarce.
Keywords
Humans, C-Reactive Protein, Risk, Cohort Studies, Longitudinal Studies, Prospective Studies, Depression, Depressive Disorder, Adolescent, Adult, Child, Female, Male
Sponsorship
Dr Khandaker acknowledges funding support from the Wellcome Trust (201486/Z/16/Z), UK Medical Research Council (MC_PC_17213), and MQ: Transforming Mental Health (MQDS17/40). PBJ acknowledges grant support from the Wellcome Trust (095844/Z/11/Z & 088869/Z/09/Z) and NIHR (RP-PG-0616-20003 and the Collaboration for Leadership in Applied Health Research & Care (CLAHRC) East of England).
Funder references
National Institute for Health Research (NIHR) (via Cambridgeshire and Peterborough NHS Foundation Trust (CPFT) (NF-SI-0514-10117)
Wellcome Trust (201486/Z/16/Z)
Wellcome Trust (095844/Z/11/Z)
Wellcome Trust (088869/Z/09/Z)
MRC (MC_PC_17213)
National Institute for Health Research (NIHR) (via Cambridgeshire and Peterborough NHS Foundation Trust (CPFT) (RP PG-0616-20003)
Embargo Lift Date
2021-01-31
Identifiers
External DOI: https://doi.org/10.1016/j.comppsych.2019.152143
This record's URL: https://www.repository.cam.ac.uk/handle/1810/298311

Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
Licence URL: https://creativecommons.org/licenses/by-nc-nd/4.0/

Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International