Automated Insulin Delivery in Adults.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Boughton, Charlotte K
Hovorka, Roman https://orcid.org/0000-0003-2901-461X
Abstract
Hybrid closed-loop (artificial pancreas) systems have recently been introduced into clinical practice for adults with type 1 diabetes. This reflects successful translation from research studies in highly supervised settings to evaluation of the technology in free-living home settings. We review the different closed-loop approaches and the key clinical evidence supporting adoption of hybrid closed-loop systems for adults with type 1 diabetes. We also discuss the growing evidence for automated insulin delivery in pregnant women and in hospitalized patients with hyperglycemia. We consider the psychosocial impact of closed-loop systems and the challenges and potential future advancements for automated insulin delivery.
Description
Keywords
Artificial pancreas, Hybrid closed-loop, Inpatient diabetes, Psychosocial impact, Type 1 diabetes, Adult, Automation, Blood Glucose, Blood Glucose Self-Monitoring, Diabetes Mellitus, Type 1, Equipment Design, Female, Hospitalization, Humans, Hyperglycemia, Insulin, Insulin Infusion Systems, Male, Pancreas, Artificial, Pregnancy, Pregnancy in Diabetics
Journal Title
Endocrinol Metab Clin North Am
Conference Name
Journal ISSN
0889-8529
1558-4410
1558-4410
Volume Title
49
Publisher
Elsevier BV
Publisher DOI
Sponsorship
National Institute of Diabetes and Digestive and Kidney Diseases (UC4DK108520)
National Institute of Diabetes and Digestive and Kidney Diseases (DP3DK112176)
National Institute of Diabetes and Digestive and Kidney Diseases (DP3DK112176)