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dc.contributor.authorBoughton, Charlotte K
dc.contributor.authorHovorka, Roman
dc.date.accessioned2020-01-07T00:31:08Z
dc.date.available2020-01-07T00:31:08Z
dc.date.issued2020-03
dc.identifier.issn0889-8529
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/300531
dc.description.abstractHybrid closed-loop (artificial pancreas) systems have recently been introduced into clinical practice for adults with type 1 diabetes. This reflects successful translation from research studies in highly supervised settings to evaluation of the technology in free-living home settings. We review the different closed-loop approaches and the key clinical evidence supporting adoption of hybrid closed-loop systems for adults with type 1 diabetes. We also discuss the growing evidence for automated insulin delivery in pregnant women and in hospitalized patients with hyperglycemia. We consider the psychosocial impact of closed-loop systems and the challenges and potential future advancements for automated insulin delivery.
dc.format.mediumPrint-Electronic
dc.languageeng
dc.publisherElsevier BV
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.subjectHumans
dc.subjectPregnancy in Diabetics
dc.subjectDiabetes Mellitus, Type 1
dc.subjectHyperglycemia
dc.subjectInsulin
dc.subjectBlood Glucose
dc.subjectBlood Glucose Self-Monitoring
dc.subjectInsulin Infusion Systems
dc.subjectHospitalization
dc.subjectEquipment Design
dc.subjectPancreas, Artificial
dc.subjectPregnancy
dc.subjectAutomation
dc.subjectAdult
dc.subjectFemale
dc.subjectMale
dc.titleAutomated Insulin Delivery in Adults.
dc.typeArticle
prism.endingPage178
prism.issueIdentifier1
prism.publicationDate2020
prism.publicationNameEndocrinol Metab Clin North Am
prism.startingPage167
prism.volume49
dc.identifier.doi10.17863/CAM.47605
rioxxterms.versionofrecord10.1016/j.ecl.2019.10.007
rioxxterms.versionAM
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2020-03
dc.contributor.orcidBoughton, Charlotte [0000-0003-3272-9544]
dc.contributor.orcidHovorka, Roman [0000-0003-2901-461X]
dc.identifier.eissn1558-4410
rioxxterms.typeJournal Article/Review
pubs.funder-project-idNational Institute of Diabetes and Digestive and Kidney Diseases (UC4DK108520)
pubs.funder-project-idNational Institute of Diabetes and Digestive and Kidney Diseases (DP3DK112176)
cam.issuedOnline2019-12-16
cam.orpheus.successThu Jan 30 10:34:29 GMT 2020 - Embargo updated
rioxxterms.freetoread.startdate2020-01-01


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International