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Further evidence for a non-cortical origin of mirror movements after stroke.

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Calautti, Cinzia 
Jones, P Simon 
Naccarato, Marcello 
Sharma, Nikhil 
Carpenter, T Adrian 

Abstract

Ejaz et al. (2018) are to be commended for showing no evidence for a cortical origin of post-stroke mirror movements. Using functional MRI during affected-finger presses in recovering adult-onset stroke patients, they found no consistent relationship between contralesional sensorimotor cortex (cSM1) activation and quantitative indices of mirror movements; specifically, mirror movements were not linked to the presence of cSM1 overactivation, arguing against the classic ‘transcallosal’ mechanism heretofore widely believed to cause mirror movements (Di Pino et al., 2014). We wish to report findings—previously published in abstract form (Calautti, 2008)—that further support the idea that mirror movements are not cortically mediated. We also present data that confirm that mirror movements can involve the affected (i.e. paretic) hand during movement of the unaffected (i.e. non-paretic) hand, also arguing in favour of disruption of a bilaterally-organized system.

Description

Keywords

Humans, Longitudinal Studies, Movement Disorders, Stroke

Journal Title

Brain

Conference Name

Journal ISSN

0006-8950
1460-2156

Volume Title

142

Publisher

Oxford University Press
Sponsorship
Medical Research Council (G0500874)