Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.
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Authors
Farhan, H
Kim, H
Johnson, P
Hughes, S
Birzele, F
Sun, G
Rutter, J
Siniakowicz, K
Weir, G
Parker, Helen
Rutter, GA
Publication Date
2011-04Journal Title
Diabetologia
ISSN
0012-186X
Volume
54
Issue
4
Pages
819-827
Language
eng
Type
Article
This Version
VoR
Physical Medium
Print-Electronic
Metadata
Show full item recordCitation
da Silva Xavier, G., Farhan, H., Kim, H., Caxaria, S., Johnson, P., Hughes, S., Bugliani, M., et al. (2011). Per-arnt-sim (PAS) domain-containing protein kinase is downregulated in human islets in type 2 diabetes and regulates glucagon secretion.. Diabetologia, 54 (4), 819-827. https://doi.org/10.1007/s00125-010-2010-7
Keywords
Islets of Langerhans, Cells, Cultured, Cell Line, Animals, Humans, Mice, Mice, Mutant Strains, Rats, Diabetes Mellitus, Type 2, Glucagon, Protein-Serine-Threonine Kinases, Glucose, Polymerase Chain Reaction, Models, Biological, Glucagon-Secreting Cells, Insulin-Secreting Cells
Sponsorship
MRC (G0600717B)
Wellcome Trust (084210/Z/07/Z)
Wellcome Trust (088357/Z/09/A)
Wellcome Trust (088357/Z/09/Z)
Identifiers
External DOI: https://doi.org/10.1007/s00125-010-2010-7
This record's URL: https://www.repository.cam.ac.uk/handle/1810/301563
Rights
Attribution-NonCommercial 4.0 International
Licence URL: https://creativecommons.org/licenses/by-nc/4.0/