Repository logo
 

Feasibility of a Mitral Annuloplasty With the Capability for Peri- and Postoperative Adjustment

Accepted version
Peer-reviewed

Type

Article

Change log

Authors

Brubert, Jacob 
Tsui, Steven 
De Sciscio, Paul 
Moggridge, Geoff D 

Abstract

jats:titleAbstract</jats:title> jats:pSurgical repair with implantation of a mitral annuloplasty ring is the gold standard treatment for mitral regurgitation. However, outcomes are variable and recurrent mitral regurgitation is not uncommon. A REshapeable Mitral Annuloplasty DevIce (REMADI) is proposed, which consists of a fully encapsulated low melting temperature alloy. The alloy is solid and rigid at body temperature and provides traction force to shape the annulus. When heated using a noncontact method, the alloy melts and the REMADI becomes malleable. The REMADI is engaged with the mitral valve annulus using anchors which automatically deploy upon contact. A passive beating porcine heart model was used to demonstrate the feasibility of the REMADI device, which was deployed, engaged, and used to reduce the diameter of the mitral valve annulus.</jats:p>

Description

Keywords

40 Engineering, 4003 Biomedical Engineering, Cardiovascular, Heart Disease, Bioengineering

Journal Title

JOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASME

Conference Name

Journal ISSN

1932-6181
1932-619X

Volume Title

14

Publisher

ASME International

Rights

All rights reserved
Sponsorship
British Heart Foundation (TG/15/4/31891)
Medical Research Council (MC_PC_15042)
Armstrong Trust