Computational Chemistry on a Budget: Supporting Drug Discovery with Limited Resources.
Accepted version
Peer-reviewed
Repository URI
Repository DOI
Change log
Authors
Willems, Henriëtte https://orcid.org/0000-0001-7196-5975
De Cesco, Stephane https://orcid.org/0000-0003-4443-4217
Svensson, Fredrik https://orcid.org/0000-0002-5556-8133
Abstract
An increasing number of new drugs have their origin in small biotech or academia. In contrast to big pharma, these environments are often more limited in terms of resources, and this necessitates different approaches to the drug discovery process. In this review, we outline how computational methods can help advance drug discovery in a setting with more limited resources and we share what, based on our experience, are the best practices for these methods.
Description
Keywords
Computational Chemistry, Drug Discovery
Journal Title
J Med Chem
Conference Name
Journal ISSN
0022-2623
1520-4804
1520-4804
Volume Title
63
Publisher
American Chemical Society (ACS)
Publisher DOI
Rights
All rights reserved
Sponsorship
Alzheimer's Research UK (ARUK-2015DDI-CAM)