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Paravalvular leakage in transcatheter mitral valve replacement: Bringing simulation theory one step closer to reality.

Accepted version
Peer-reviewed

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Type

Article

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Authors

Weir-McCall, Jonathan R 
Kotnik, Marusa 

Abstract

Transcatheter mitral valve replacement (TMVR) has emerged as a promising technique for the treatment of these patients with severe mitral valve disease and high or prohibitive surgical risk. Early experience with TMVR has shown a high rate of technical success and promising reductions in the severity of mitral regurgitation sustained out to 1 year post procedure. Despite this, procedural complications remain high, with the most common and significant of these being valve embolization, left ventricualr outflow tract (LVOT) obstruction and paravalvular leakage (PVL). It is this currently unanswered question that Morris et al. start to address in this issue of the Journal. They use the same annular segmentation and valve simulation as already proposed to predict LVOT obstruction, but use it to focus instead on examining the residual gap left between the base of the simulated transcatheter valve and the mitral leaflets or surgical prosthesis.

Description

Keywords

Computed tomography, Mitral valve, Structural intervention, Cardiac Catheterization, Heart Valve Prosthesis, Heart Valve Prosthesis Implantation, Humans, Mitral Valve, Mitral Valve Insufficiency, Predictive Value of Tests, Treatment Outcome, Ventricular Outflow Obstruction

Journal Title

J Cardiovasc Comput Tomogr

Conference Name

Journal ISSN

1934-5925
1876-861X

Volume Title

14

Publisher

Elsevier BV