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dc.contributor.authorWoronik, Alyssa
dc.contributor.authorTunström, Kalle
dc.contributor.authorPerry, Michael W.
dc.contributor.authorNeethiraj, Ramprasad
dc.contributor.authorStefanescu, Constanti
dc.contributor.authorCelorio-Mancera, Maria de la Paz
dc.contributor.authorBrattström, Oskar
dc.contributor.authorHill, Jason
dc.contributor.authorLehmann, Philipp
dc.contributor.authorKäkelä, Reijo
dc.contributor.authorWheat, Christopher W.
dc.date.accessioned2020-12-22T18:55:47Z
dc.date.available2020-12-22T18:55:47Z
dc.date.issued2019-12-17
dc.date.submitted2019-06-29
dc.identifier.others41467-019-13596-2
dc.identifier.other13596
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/315421
dc.descriptionFunder: Department of Zoology at Stockholm University; Erik Philip-Sorensens Foundation; The Academy of Finland,131155
dc.description.abstractAbstract: Tradeoffs affect resource allocation during development and result in fitness consequences that drive the evolution of life history strategies. Yet despite their importance, we know little about the mechanisms underlying life history tradeoffs. Many species of Colias butterflies exhibit an alternative life history strategy (ALHS) where females divert resources from wing pigment synthesis to reproductive and somatic development. Due to this reallocation, a wing color polymorphism is associated with the ALHS: either yellow/orange or white. Here we map the locus associated with this ALHS in Colias crocea to a transposable element insertion located downstream of the Colias homolog of BarH-1, a homeobox transcription factor. Using CRISPR/Cas9 gene editing, antibody staining, and electron microscopy we find white-specific expression of BarH-1 suppresses the formation of pigment granules in wing scales and gives rise to white wing color. Lipid and transcriptome analyses reveal physiological differences associated with the ALHS. Together, these findings characterize a mechanism for a female-limited ALHS.
dc.languageen
dc.publisherNature Publishing Group UK
dc.subjectArticle
dc.subject/631/181
dc.subject/631/181/2806
dc.subject/631/181/2474
dc.subject/38
dc.subject/38/1
dc.subject/38/91
dc.subject/101
dc.subject/101/28
dc.subject/49
dc.subject/45
dc.subject/45/43
dc.subject/14
dc.subject/45/23
dc.subject/14/19
dc.subjectarticle
dc.titleA transposable element insertion is associated with an alternative life history strategy
dc.typeArticle
dc.date.updated2020-12-22T18:55:46Z
prism.issueIdentifier1
prism.publicationNameNature Communications
prism.volume10
dc.identifier.doi10.17863/CAM.62528
dcterms.dateAccepted2019-11-15
rioxxterms.versionofrecord10.1038/s41467-019-13596-2
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidTunström, Kalle [0000-0002-5285-1531]
dc.contributor.orcidPerry, Michael W. [0000-0002-5977-8031]
dc.contributor.orcidCelorio-Mancera, Maria de la Paz [0000-0003-0296-0577]
dc.contributor.orcidBrattström, Oskar [0000-0002-2266-0304]
dc.contributor.orcidLehmann, Philipp [0000-0001-8344-6830]
dc.identifier.eissn2041-1723
pubs.funder-project-idVetenskapsrådet (Swedish Research Council) (2012–3715)
pubs.funder-project-idKnut och Alice Wallenbergs Stiftelse (Knut and Alice Wallenberg Foundation) (2012.0058)


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