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dc.contributor.authorOlsen, Alexander
dc.contributor.authorBabikian, Talin
dc.contributor.authorBigler, Erin D.
dc.contributor.authorCaeyenberghs, Karen
dc.contributor.authorConde, Virginia
dc.contributor.authorDams-O’Connor, Kristen
dc.contributor.authorDobryakova, Ekaterina
dc.contributor.authorGenova, Helen
dc.contributor.authorGrafman, Jordan
dc.contributor.authorHåberg, Asta K.
dc.contributor.authorHeggland, Ingrid
dc.contributor.authorHellstrøm, Torgeir
dc.contributor.authorHodges, Cooper B.
dc.contributor.authorIrimia, Andrei
dc.contributor.authorJha, Ruchira M.
dc.contributor.authorJohnson, Paula K.
dc.contributor.authorKoliatsos, Vassilis E.
dc.contributor.authorLevin, Harvey
dc.contributor.authorLi, Lucia M.
dc.contributor.authorLindsey, Hannah M.
dc.contributor.authorLivny, Abigail
dc.contributor.authorLøvstad, Marianne
dc.contributor.authorMedaglia, John
dc.contributor.authorMenon, David K.
dc.contributor.authorMondello, Stefania
dc.contributor.authorMonti, Martin M.
dc.contributor.authorNewcombe, Virginia F.J.
dc.contributor.authorPetroni, Agustin
dc.contributor.authorPonsford, Jennie
dc.contributor.authorSharp, David
dc.contributor.authorSpitz, Gershon
dc.contributor.authorWestlye, Lars T.
dc.contributor.authorThompson, Paul M.
dc.contributor.authorDennis, Emily L.
dc.contributor.authorTate, David F.
dc.contributor.authorWilde, Elisabeth A.
dc.contributor.authorHillary, Frank G.
dc.date.accessioned2021-04-08T15:33:09Z
dc.date.available2021-04-08T15:33:09Z
dc.date.issued2020-08-14
dc.identifier.issn1931-7557
dc.identifier.others11682-020-00313-7
dc.identifier.other313
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/319592
dc.description.abstractAbstract: The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is significant, and the heterogeneity of TBI patients and the relatively small sample sizes of most current neuroimaging studies is a major challenge for scientific advances and clinical translation. The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Adult moderate/severe TBI (AMS-TBI) working group aims to be a driving force for new discoveries in AMS-TBI by providing researchers world-wide with an effective framework and platform for large-scale cross-border collaboration and data sharing. Based on the principles of transparency, rigor, reproducibility and collaboration, we will facilitate the development and dissemination of multiscale and big data analysis pipelines for harmonized analyses in AMS-TBI using structural and functional neuroimaging in combination with non-imaging biomarkers, genetics, as well as clinical and behavioral measures. Ultimately, we will offer investigators an unprecedented opportunity to test important hypotheses about recovery and morbidity in AMS-TBI by taking advantage of our robust methods for large-scale neuroimaging data analysis. In this consensus statement we outline the working group’s short-term, intermediate, and long-term goals.
dc.languageen
dc.publisherSpringer US
dc.subjectSi: Enigma Tbi
dc.subjectBrain injury
dc.subjectRadiology
dc.subjectOpen Science
dc.subjectNeurodegeneration
dc.subjectRehabilitation
dc.subjectENIGMA
dc.titleToward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group
dc.typeArticle
dc.date.updated2021-04-08T15:33:08Z
prism.endingPage554
prism.issueIdentifier2
prism.publicationNameBrain Imaging and Behavior
prism.startingPage526
prism.volume15
dc.identifier.doi10.17863/CAM.66712
rioxxterms.versionofrecord10.1007/s11682-020-00313-7
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://creativecommons.org/licenses/by/4.0/
dc.contributor.orcidOlsen, Alexander [0000-0001-8691-3860]
dc.identifier.eissn1931-7565
pubs.funder-project-idSee acknowledgement section in manuscript for all relevant funding info for all authors (1)


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