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dc.contributor.authorAhuno, Samuel Terkper
dc.contributor.authorDoebley, Anna-Lisa
dc.contributor.authorAhearn, Thomas U
dc.contributor.authorYarney, Joel
dc.contributor.authorTitiloye, Nicholas
dc.contributor.authorHamel, Nancy
dc.contributor.authorAdjei, Ernest
dc.contributor.authorClegg-Lamptey, Joe-Nat
dc.contributor.authorEdusei, Lawrence
dc.contributor.authorAwuah, Baffour
dc.contributor.authorSong, Xiaoyu
dc.contributor.authorVanderpuye, Verna
dc.contributor.authorAbubakar, Mustapha
dc.contributor.authorDuggan, Maire
dc.contributor.authorStover, Daniel G
dc.contributor.authorNyarko, Kofi
dc.contributor.authorBartlett, John MS
dc.contributor.authorAitpillah, Francis
dc.contributor.authorAnsong, Daniel
dc.contributor.authorGardner, Kevin L
dc.contributor.authorBoateng, Felix Andy
dc.contributor.authorBowcock, Anne M
dc.contributor.authorCaldas, Carlos
dc.contributor.authorFoulkes, William D
dc.contributor.authorWiafe, Seth
dc.contributor.authorWiafe-Addai, Beatrice
dc.contributor.authorGarcia-Closas, Montserrat
dc.contributor.authorKwarteng, Alexander
dc.contributor.authorHa, Gavin
dc.contributor.authorFigueroa, Jonine D
dc.contributor.authorPolak, Paz
dc.contributor.authorGhana Breast Health Study Team
dc.date.accessioned2021-10-19T23:30:34Z
dc.date.available2021-10-19T23:30:34Z
dc.date.issued2021-09-17
dc.identifier.issn2397-768X
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/329638
dc.description.abstractCirculating tumor DNA (ctDNA) sequencing studies could provide novel insights into the molecular pathology of cancer in sub-Saharan Africa. In 15 patient plasma samples collected at the time of diagnosis as part of the Ghana Breast Health Study and unselected for tumor grade and subtype, ctDNA was detected in a majority of patients based on whole- genome sequencing at high (30×) and low (0.1×) depths. Breast cancer driver copy number alterations were observed in the majority of patients.
dc.format.mediumElectronic
dc.languageeng
dc.publisherSpringer Science and Business Media LLC
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.subjectGhana Breast Health Study Team
dc.titleCirculating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa.
dc.typeArticle
prism.issueIdentifier1
prism.publicationDate2021
prism.publicationNameNPJ Precis Oncol
prism.startingPage83
prism.volume5
dc.identifier.doi10.17863/CAM.77087
dcterms.dateAccepted2021-07-21
rioxxterms.versionofrecord10.1038/s41698-021-00219-7
rioxxterms.versionVoR
rioxxterms.licenseref.urihttp://www.rioxx.net/licenses/all-rights-reserved
rioxxterms.licenseref.startdate2021-09-17
dc.contributor.orcidDoebley, Anna-Lisa [0000-0002-3371-3352]
dc.contributor.orcidAbubakar, Mustapha [0000-0003-3728-6535]
dc.contributor.orcidDuggan, Maire [0000-0001-6625-7683]
dc.contributor.orcidBartlett, John MS [0000-0002-0347-3888]
dc.contributor.orcidAitpillah, Francis [0000-0001-9495-6887]
dc.contributor.orcidCaldas, Carlos [0000-0003-3547-1489]
dc.contributor.orcidFoulkes, William D [0000-0001-7427-4651]
dc.contributor.orcidWiafe, Seth [0000-0001-6085-9405]
dc.contributor.orcidHa, Gavin [0000-0001-7578-7272]
dc.contributor.orcidFigueroa, Jonine D [0000-0002-5100-623X]
dc.contributor.orcidPolak, Paz [0000-0002-2153-4488]
dc.identifier.eissn2397-768X
rioxxterms.typeJournal Article/Review
cam.issuedOnline2021-09-17


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International