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dc.contributor.authorSwift, Benjamin Michael Connor
dc.contributor.authorBarron, Elsa Sandoval
dc.contributor.authorChristley, Rob
dc.contributor.authorCorbetta, Davide
dc.contributor.authorGrau-Roma, Llorenç
dc.contributor.authorJewell, Chris
dc.contributor.authorO'Cathail, Colman
dc.contributor.authorMitchell, Andy
dc.contributor.authorPhoenix, Jess
dc.contributor.authorProsser, Alison
dc.contributor.authorRees, Catherine
dc.contributor.authorSorley, Marion
dc.contributor.authorVerin, Ranieri
dc.contributor.authorBennett, Malcolm
dc.date.accessioned2022-01-06T11:52:00Z
dc.date.available2022-01-06T11:52:00Z
dc.date.issued2021-10-25
dc.identifier.issn2045-2322
dc.identifier.otherPMC8545939
dc.identifier.other34697381
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/332176
dc.description.abstractBovine tuberculosis (bTB) is an important animal health and economic problem for the cattle industry and a potential zoonotic threat. Wild badgers (Meles meles) play a role on its epidemiology in some areas of high prevalence in cattle, particularly in the UK and Republic of Ireland and increasingly in parts of mainland Europe. However, little is known about the involvement of badgers in areas on the spatial edge of the cattle epidemic, where increasing prevalence in cattle is seen. Here we report the findings of a study of found-dead (mainly road-killed) badgers in six counties on the edge of the English epidemic of bTB in cattle. The overall prevalence of Mycobacterium tuberculosis complex (MTC) infection detected in the study area was 51/610 (8.3%, 95% CI 6.4-11%) with the county-level prevalence ranging from 15 to 4-5%. The MTC spoligotypes of recovered from badgers and cattle varied: in the northern part of the study area spoligotype SB0129 predominated in both cattle and badgers, but elsewhere there was a much wider range of spoligotypes found in badgers than in cattle, in which infection was mostly with the regional cattle spoligotype. The low prevalence of MTC in badgers in much of the study area, and, relative to in cattle, the lower density of sampling, make firm conclusions difficult to draw. However, with the exception of Cheshire (north-west of the study area), little evidence was found to link the expansion of the bTB epidemic in cattle in England to widespread badger infection.
dc.languageeng
dc.publisherSpringer Science and Business Media LLC
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.sourceessn: 2045-2322
dc.sourcenlmid: 101563288
dc.titleTuberculosis in badgers where the bovine tuberculosis epidemic is expanding in cattle in England.
dc.typeArticle
dc.date.updated2022-01-06T11:51:58Z
prism.issueIdentifier1
prism.publicationNameSci Rep
prism.volume11
dc.identifier.doi10.17863/CAM.79622
dcterms.dateAccepted2021-09-09
rioxxterms.versionofrecord10.1038/s41598-021-00473-6
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by/4.0/
dc.identifier.eissn2045-2322
pubs.funder-project-idResearch England (CCF-17-7779)
pubs.funder-project-idDepartment for Environment, Food and Rural Affairs, UK Government (SE3054 / OJEU 28406)
cam.issuedOnline2021-10-25


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Attribution 4.0 International
Except where otherwise noted, this item's licence is described as Attribution 4.0 International