Show simple item record

dc.contributor.authorJones, Rebecca
dc.contributor.authorMueller, J
dc.contributor.authorSharp, SJ
dc.contributor.authorDuschinsky, R
dc.contributor.authorGriffin, SJ
dc.contributor.authorAhern, AL
dc.description.abstractIntroduction: On average, aspects of mental health improve following behavioural weight management programmes, yet this is not the case for all participants. It is important to identify those at risk of harm to provide more effective psychological support. We aimed to identify participant characteristics associated with changes in depression and anxiety in participants of a behavioural weight management programme. Methods: In the Weight loss Referrals for Adults in Primary care (WRAP) trial, 1267 adults with BMI≥28 kg/m2 were randomised to brief intervention, or WW (formerly Weight Watchers) for 12-weeks or 52-weeks and followed for five years. We used linear and multinomial regression to explore the association between participant characteristics and changes in depression and anxiety (measured by Hospital Anxiety and Depression Scale). Where possible, the impact of missing data was investigated using multiple imputation. Results: Higher baseline anxiety was associated with decreases in anxiety symptoms and increases in depression symptoms from baseline to follow-up. Higher baseline depression was associated with decreases in depression symptoms and increases in anxiety symptoms from baseline to follow-up. The magnitude of the associations were small. No further characteristics were consistently associated with changes in mental health. Discussion: Evidence suggests that baseline depression and anxiety may indicate how depression and anxiety symptoms change during and after attending WW. Measurement of depression and anxiety at the start of a behavioural weight management programme and subsequent monitoring may facilitate timely psychological support if a deterioration in mental health is identified. Further research in large and diverse participant samples is required to clarify the findings.
dc.description.sponsorshipThe WRAP trial was funded by the National Prevention Research Initiative through research grant MR/J000493. The intervention was provided by WW (formerly Weight Watchers) at no cost via an MRC Industrial Collaboration Award. Five year follow up of the WRAP trial was funded by the National Institute for Health Research (NIHR) under its Programme Grants for Applied Research Programme (RP-PG-0216-20010). RAJ, ALA, SJG, and SJS are supported by the Medical Research Council (MRC) (Grant MC_UU_00006/6). The University of Cambridge has received salary support in respect of SJG from the National Health Service in the East of England through the Clinical Academic Reserve.
dc.publisherS. Karger AG
dc.rightsAttribution-NonCommercial 4.0 International
dc.subjectMental health
dc.subjectWeight management
dc.subjectCognitive Behavioral Therapy
dc.subjectMental Health
dc.subjectWeight Reduction Programs
dc.titleParticipant characteristics associated with changes in mental health in a trial of behavioural weight management programmes: Secondary analysis of the WRAP trial
dc.publisher.departmentMrc Epidemiology Unit Student
prism.publicationNameObesity Facts: the European journal of obesity
dc.contributor.orcidJones, Beckie [0000-0003-2197-1175]
dc.contributor.orcidMueller, Julia [0000-0002-4939-7112]
dc.contributor.orcidSharp, Stephen [0000-0003-2375-1440]
dc.contributor.orcidDuschinsky, Robbie [0000-0003-2023-5328]
dc.contributor.orcidGriffin, Simon [0000-0002-2157-4797]
dc.contributor.orcidAhern, Amy [0000-0001-5069-4758]
rioxxterms.typeJournal Article/Review
pubs.funder-project-idMRC (MC_UU_00006/6)
pubs.funder-project-idDepartment of Health (via National Institute for Health Research (NIHR)) (RP-PG-0216-20010)
pubs.funder-project-idMRC (unknown)
pubs.funder-project-idMedical Research Council (MC_UU_12015/4)
cam.orpheus.success2022-07-06: VoR added
pubs.licence-display-nameApollo Repository Deposit Licence Agreement

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial 4.0 International