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dc.contributor.authorWalters, Ben
dc.contributor.authorGaskell, Peter
dc.contributor.authorMuzaffar, Sayed
dc.contributor.authorIftikhar, Haissan
dc.contributor.authorMonksfield, Peter
dc.contributor.authorBance, Manohar
dc.date.accessioned2022-03-19T02:06:01Z
dc.date.available2022-03-19T02:06:01Z
dc.date.issued2022-02
dc.identifier.issn2378-8038
dc.identifier.other35155802
dc.identifier.otherPMC8823255
dc.identifier.urihttps://www.repository.cam.ac.uk/handle/1810/335198
dc.description.abstractOBJECTIVES: As the population ages and implantation criteria are relaxed, more patients with complex comorbidities are becoming eligible for cochlear implantation (CI). These patients have higher risks associated with general anesthesia. This systematic review assesses outcomes and complications following CI under local anesthetic to examine utility for patients deemed not suitable or at high risk for general anesthesia. METHODS: A systematic review and meta-analysis performed according to the 2020 PRISMA guidelines. Databases searched were MEDLINE, PubMed, EMBASE, CINAHL, Web of Science Core Collection, Cochrane Database of Systematic Reviews, and Cochrane Central Register of Controlled Trials and ClinicalTrials.gov. There were no limitations on year of publication or language. RESULTS: Then, 132 unique were identified. After screening abstracts and full texts for eligibility criteria a total of 18 articles were included. In the nine studies where audiological data were reported, all patients demonstrated improvement in audiological outcomes following implantation under local anesthetic (LA). Only minor complications of transient vertigo, wound infection, facial nerve paralysis, confusion, and tinnitus were reported but all were transient. Meta-analysis showed surgical time was significantly shorter under LA. CONCLUSIONS: CI under LA is safe for patients with comorbidities which preclude them from general anesthesia, with minimal complications and an improved cost-effectiveness profile. However, larger scale, robust trials are required to assess this further.
dc.languageeng
dc.publisherWiley
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceessn: 2378-8038
dc.sourcenlmid: 101684963
dc.subjectLocal anesthetic
dc.subjectCochlear Implantation
dc.subjectConscious Sedation
dc.titleCochlear implantation under local anesthetic: A systematic review and meta-analysis.
dc.typeArticle
dc.date.updated2022-03-19T02:06:00Z
prism.endingPage236
prism.issueIdentifier1
prism.publicationNameLaryngoscope Investig Otolaryngol
prism.startingPage226
prism.volume7
dc.identifier.doi10.17863/CAM.82628
dcterms.dateAccepted2021-12-11
rioxxterms.versionofrecord10.1002/lio2.720
rioxxterms.versionVoR
rioxxterms.licenseref.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.contributor.orcidWalters, Ben [0000-0002-5208-6446]
dc.contributor.orcidGaskell, Peter [0000-0002-3187-5569]
dc.contributor.orcidMuzaffar, Sayed [0000-0003-3065-0269]
dc.contributor.orcidIftikhar, Haissan [0000-0003-3266-4015]
dc.contributor.orcidMonksfield, Peter [0000-0001-7343-7105]
dc.contributor.orcidBance, Manohar [0000-0001-8050-3617]
dc.identifier.eissn2378-8038
cam.issuedOnline2022-01-05


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Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International