Beyond Platonic: How to Build Metal-Organic Polyhedra Capable of Binding Low-Symmetry, Information-Rich Molecular Cargoes.
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Publication Date
2022-06-08Journal Title
Chem Rev
ISSN
0009-2665
Publisher
American Chemical Society (ACS)
Type
Article
This Version
AM
Metadata
Show full item recordCitation
McTernan, C. T., Davies, J. A., & Nitschke, J. R. (2022). Beyond Platonic: How to Build Metal-Organic Polyhedra Capable of Binding Low-Symmetry, Information-Rich Molecular Cargoes.. Chem Rev https://doi.org/10.1021/acs.chemrev.1c00763
Abstract
The field of metallosupramolecular chemistry has advanced rapidly in recent years. Much work in this area has focused on the formation of hollow self-assembled metal-organic architectures and exploration of the applications of their confined nanospaces. These discrete, soluble structures incorporate metal ions as 'glue' to link organic ligands together into polyhedra.Most of the architectures employed thus far have been highly symmetrical, as these have been the easiest to prepare. Such high-symmetry structures contain pseudospherical cavities, and so typically bind roughly spherical guests. Biomolecules and high-value synthetic compounds are rarely isotropic, highly-symmetrical species. To bind, sense, separate, and transform such substrates, new, lower-symmetry, metal-organic cages are needed. Herein we summarize recent approaches, which taken together form the first draft of a handbook for the design of higher-complexity, lower-symmetry, self-assembled metal-organic architectures.
Sponsorship
European Research Council
Leverhulme Trust
The Isaac Newton Trust
Sidney Sussex College, Cambridge
Funder references
Engineering and Physical Sciences Research Council (EP/P027067/1)
EPSRC (EP/T031603/1)
European Research Council (695009)
Embargo Lift Date
2023-04-18
Identifiers
External DOI: https://doi.org/10.1021/acs.chemrev.1c00763
This record's URL: https://www.repository.cam.ac.uk/handle/1810/335748
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