Gene reporters for magnetic resonance imaging.

Thumbnail
View / Open Files
Authors
Brindle, Kevin M
Publication Date
2022-10
Journal Title
Trends Genet
ISSN
0168-9525
Publisher
Elsevier BV
Type
Article
This Version
AM
Metadata
Show full item record
Citation
Brindle, K. M. (2022). Gene reporters for magnetic resonance imaging.. Trends Genet https://doi.org/10.1016/j.tig.2022.05.006
Abstract
MRI-based gene reporters allow imaging of gene expression at depth (tens of centimetres) and at relatively high resolution (~10-100 μm) and have the potential to be translated to the clinic. The reporters exploit either endogenous contrast mechanisms or they modulate the response to an introduced exogenous contrast agent.
Keywords
MRI, diffusion, exchange, gene reporters, relaxation, Genes, Reporter, Image Enhancement, Magnetic Resonance Imaging
Sponsorship
Cancer Research UK
Funder references
Cancer Research UK (CB4100)
Cancer Research UK (C14303/A17197)
Embargo Lift Date
2023-05-28
Identifiers
External DOI: https://doi.org/10.1016/j.tig.2022.05.006
This record's URL: https://www.repository.cam.ac.uk/handle/1810/338350
Rights
Attribution-NonCommercial-NoDerivatives 4.0 International
Licence URL: https://creativecommons.org/licenses/by-nc-nd/4.0/
Statistics



Total file downloads (since January 2020). For more information on metrics see the IRUS guide.

Attribution-NonCommercial-NoDerivatives 4.0 International
Except where otherwise noted, this item's licence is described as Attribution-NonCommercial-NoDerivatives 4.0 International