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Raw data supporting 'Decreased Water Mobility Contributes To Increased Alpha-Synuclein Aggregation'


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Authors

Stephens, Amberley Stephens  ORCID logo  https://orcid.org/0000-0002-7303-6392
Kölbel, Johanna 
Moons, Rani 
Ruggerio, Michael 
Mahmoudi, Najet 

Description

Raw data files supporting the manuscript 'Decreased Water Mobility Contributes To Increased Alpha-Synuclein Aggregation'. One excel file (.xlsx) contains raw data supporting each figure. Figure 1, ThT based aggregation kinetics, data for the average of 4 wells from 3 experiments. Table 1, 3 data points for t50, tlag, % fluorescence and 6 wells for remaining monomer. Figure 2, THz average of 8 measurements for four conditions. Figure 3a+c, MS, average of 3 measurements. Figure 3b+4a+Suppl Fig.9, NMR 1 measurement of four conditions with assignments. Figure 4b, THz average of 3 measurements. Suppl. Fig. 4, height measurements from AFM of 8 fibrils. Suppl. Fig 5, radial pair distribution functions from AIMD simulations. Suppl. Fig 7+8, MS data from three repeats. SANS data is provided by a separate DOI fond in the manuscript.

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Data is provided in an excel sheet

Keywords

Amyloid, Mass spectrometry, Nuclear Magnetic Resonance, Solvation, Terahertz spectroscopy

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