Department of Chemistry
About this community
News
(c) All rights reserved.
Sub-communities within this community
Collections in this community
-
Early Digital Chemical Objects
Digital chemical artefacts created in the early 1990s
Recent Submissions
-
Backbone conformation affects duplex initiation and duplex propagation in hybridisation of synthetic H-bonding oligomers.
(Royal Society of Chemistry (RSC), 2018-06)Synthetic oligomers equipped with complementary H-bond donor and acceptor side chains form multiply H-bonded duplexes in organic solvents. Comparison of the duplex forming properties of four families of oligomers with ... -
Structural Properties of α-Synuclein in Functional and Pathological Contexts
(2016-11-26)α-synuclein (αS) is an intrinsically disordered protein that is strongly connected with Parkinson’s disease (PD) and a number of other neurodegenerative disorders, including Parkinson’s disease with dementia, dementia with ... -
Prediction of Metabolic Stability and Bioavailability with Bioisosteric Replacements
(2018-01-01)Drug development is a long and expensive process. Potential drug candidates can fail clinical trials due to numerous issues, including metabolic stability and efficacy issues, wasting years of research effort and resource. ...
