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  Alterations in the Ca2+ toolkit in oesophageal adenocarcinoma. 

  Cutliffe, Alana L; McKenna, Sharon L; Chandrashekar, Darshan S; Ng, Alvin; Devonshire, Ginny; Fitzgerald, Rebecca C; O'Donovan, Tracey RMackrill, John J et al. (Open Exploration Publishing, 2021)

  Aim: To investigate alterations in transcription of genes, encoding Ca2+ toolkit proteins, in oesophageal adenocarcinoma (OAC) and to assess associations between gene expression, tumor grade, nodal-metastatic stage, and ...
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  Genetic Evidence for Protective Effects of Angiotensin-Converting Enzyme Against Alzheimer Disease But Not Other Neurodegenerative Diseases in European Populations. 

  Ryan, David K; Karhunen, Ville; Su, Bowen; Traylor, Matthew; Richardson, Tom G; Burgess, Stephen; Tzoulaki, IoannaGill, Dipender et al. (2022-08-29)

  <h4>Background and objectives</h4>Angiotensin-converting enzyme (ACE) inhibitors are a commonly prescribed class of medication used to treat heart failure, hypertension, and chronic kidney disease. However, previous ...
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  Views of advance care planning in older hospitalized patients following an emergency admission: A qualitative study. 

  Bielinska, Anna-Maria; Soosaipillai, Gehan; Riley, Julia; Darzi, Ara; Urch, Catherine; Archer, Stephanie (2022-09-01)

  <h4>Background</h4>There is increasing evidence of the need to consider advance care planning (ACP) for older adults who have been recently admitted to hospital as an emergency. However, there is a gap in knowledge regarding ...
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  Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia. 

  Sogorb-Esteve, Aitana; Nilsson, Johanna; Swift, Imogen J; Heller, Carolin; Bocchetta, Martina; Russell, Lucy L; Peakman, GeorgiaConvery, Rhian Svan Swieten, John CSeelaar, HarroBorroni, BarbaraGalimberti, DanielaSanchez-Valle, RaquelLaforce, RobertMoreno, FerminSynofzik, MatthisGraff, CarolineMasellis, MarioTartaglia, Maria CarmelaRowe, James BVandenberghe, RikFinger, ElizabethTagliavini, FabrizioSantana, IsabelButler, Chris RDucharme, SimonGerhard, AlexanderDanek, AdrianLevin, JohannesOtto, MarkusSorbi, SandroLe Ber, IsabellePasquier, FlorenceGobom, JohanBrinkmalm, AnnBlennow, KajZetterberg, HenrikRohrer, Jonathan D et al. (2022-08-31)

  <h4>Background</h4>Approximately a third of frontotemporal dementia (FTD) is genetic with mutations in three genes accounting for most of the inheritance: C9orf72, GRN, and MAPT. Impaired synaptic health is a common mechanism ...

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