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  Human osteoarthritic synovial fluid increases excitability of mouse dorsal root ganglion sensory neurons: an in-vitro translational model to study arthritic pain. 

  Chakrabarti, Sampurna; Jadon, Deepak; Bulmer, David; Smith, Ewan

  Objectives: Knee osteoarthritis is a leading global cause of morbidity. This study investigates the effects of knee synovial fluid from patients with osteoarthritis (OA-SF) on the activity of dorsal root ganglion sensory ...
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  Self-assembly of embryonic and two extra-embryonic stem cell types into gastrulating embryo-like structures. 

  Sozen, Berna; Amadei, Gianluca; Cox, Andy; Wang, Ran; Na, Ellen; Czukiewska, Sylwia; Chappell, LiaVoet, ThierryMichel, GeertJing, NaiheGlover, DavidZernicka-Goetz, Magdalena et al. (Springer Nature, 2018-08)

  Embryonic stem (ES) cells can be incorporated into the developing embryo and its germ line but when cultured alone, their ability to generate embryonic structures is restricted. They can interact with trophoblast stem (TS) ...
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  ERβ-mediated induction of cystatins results in suppression of TGFβ signaling and inhibition of triple-negative breast cancer metastasis. 

  Reese, Jordan M; Bruinsma, Elizabeth S; Nelson, Adam W; Chernukhin, Igor; Carroll, Jason; Li, Ying; Subramaniam, MalayannanSuman, Vera JNegron, VivianMonroe, David GIngle, James NGoetz, Matthew PHawse, John R et al. (2018-10)

  Triple-negative breast cancer (TNBC) accounts for a disproportionately high number of deaths due to a lack of targeted therapies and an increased likelihood of distant recurrence. Estrogen receptor beta (ERβ), a ...
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  Durability enhancements using fabric formwork 

  Orr, John; Darby, Antony; Ibell, Timothy; Evernden, Mark

  By replacing conventional concrete moulds with flexible sheets of permeable fabric the construction of optimised concrete elements that provide material savings of up to 40% when compared to an equivalent strength prismatic ...

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