Recent advances in epilepsy


Type
Article
Change log
Authors
Manford, M 
Abstract

This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics and underlying mechanisms, including status epilepticus, drug and surgical treatments. Lessons from rarer epilepsies regarding the relationship between epilepsy type, mechanisms and choice of antiepileptic drugs (AED) are explored and data regarding AED use in pregnancy are reviewed. Concepts evolving towards a move from treating seizures to treating epilepsy are discussed, both in terms of the mechanisms of epileptogenesis, and in terms of epilepsy’s broader comorbidity, especially depression.

Description
Keywords
epilepsy, classification, status epilepticus, treatment, pregnancy, epileptogenesis
Journal Title
Journal of Neurology
Conference Name
Journal ISSN
0340-5354
1432-1459
Volume Title
Publisher
Springer