Optimal cerebral perfusion pressure via transcranial Doppler in TBI: application of robotic technology.


Type
Article
Change log
Authors
Zeiler, Frederick A  ORCID logo  https://orcid.org/0000-0003-1737-0510
Czosnyka, Marek 
Smielewski, Peter 
Abstract

Individualized cerebral perfusion pressure (CPP) targets may be derived via assessing the minimum of the parabolic relationship between an index of cerebrovascular reactivity and CPP. This minimum is termed the optimal CPP (CPPopt), and literature suggests that the further away CPP is from CPPopt, the worse is clinical outcome in adult traumatic brain injury (TBI). Typically, CPPopt estimation is based on intracranial pressure (ICP)-derived cerebrovascular reactivity indices, given ICP is commonly measured and provides continuous long duration data streams. The goal of this study is to describe for the first time the application of robotic transcranial Doppler (TCD) and the feasibility of determining CPPopt based on TCD autoregulation indices.

Description
Keywords
CPP optimum, Robotic transcranial Doppler, TBI, TCD, Traumatic brain injury, Brain Injuries, Traumatic, Cerebrovascular Circulation, Humans, Robotics, Ultrasonography, Doppler
Journal Title
Acta Neurochir (Wien)
Conference Name
Journal ISSN
0001-6268
0942-0940
Volume Title
160
Publisher
Springer Science and Business Media LLC