Integrated functional genomic screening to bypass TKI resistance in chronic myeloid leukemia.
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Peer-reviewed
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Abstract
CML is readily treatable with tyrosine kinase inhibitors (TKIs); however, resistance occurs, with the disease curable in only ∼15%-20% of patients. Using integrated functional genomics, Adnan Awad et al.1 identify agents effective against CML stem cells and describe mechanisms underlying TKI resistance.
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Cell Rep Med
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2666-3791
2666-3791
2666-3791
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5
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Elsevier
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Except where otherwised noted, this item's license is described as Attribution 4.0 International (CC BY 4.0)